Discover and read the best of Twitter Threads about #angiogenesis

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How wounds heal

#woundhealing #injury #homeostasis #angiogenesis #epidermal #skin #MedTwitter #meded #foamed #InnoMed

Timelapse Of A Wound Healing
#epidermal #medtwitter #meded #foamed #InnoMed #homeostasis #injuy #woundhealing #sciencetwitter

How does #aging affect #WoundHealing?
#scRNAseq identifies major changes in cell compositions, kinetics, and molecular profiles during #woundhealing in aged #skin @CellReports
bit.ly/3PZMies
#epidermal #MedTwitter #meded #foamed #InnoMed #bioinformatics #homeostasis
Read 4 tweets
I'm very excited to share my very first paper!!💜

In our work in @ActaBio we propose a more sophisticated way of validating #3D #TractionForceMicroscopy methods and we apply our novel inverse method to an in vitro model of #angiogenesis (1/10)
👇👇🧵

sciencedirect.com/science/articl…
Typically, TFM methods are validated under simplified scenarios (using simplified cell geometries, arbitrarily choosing force exertion points, or bypassing image processing steps). Here, we designed a simulation platform that is as close as possible to a real case. (2/10)
We used the geometry of a real angiogenic sprout via confocal microscopy. We simulated focal adhesions of varying size and distribution (to see how the accuracy is affected by it) and generated different ground truth displacements and tractions. (3/10) Image
Read 11 tweets
Key: "The observed pulmonary vascular dilation might be due to relative failure of normal, physiological hypoxic pulmonary vasoconstriction in the setting of overactivation of a regional vasodilatation cascade as part of a dysfunctional and diffuse inflammatory process." 2/
This leads me to hypothesize this is the site of viral injury, where #COVID binds #ACE2R's - where mito demands are the greatest - where #HIF proteins and assoc. cascades they initiate are in play - including #vasodialiation #angiogenesis and excessive #inflammation 3/
Read 21 tweets

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