Discover and read the best of Twitter Threads about #apobec

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Ash Alizadeh, MD/PhD 🇺🇸
@AshAlizadeh
Delighted to share our new study nature.com/articles/s4158… introducing PhasED-Seq out today @NatureBiotech.
A fantastic collaboration from @StanfordMedicine led by Dave_Kurtz & Joanne Soo with @max_diehn to help transform #cancer interception & monitoring by improving #LiquidBiopsy #ctDNA detection of #MRD.
For many cancers & nearly all currently available techniques, the impressive KM plots of #ctDNA #MRD immediately after definitive Rx w/ curative-intent unfortunately still miss ~50% of all events which occur in the MRD-negative subset, thus having modest NPV.
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#cfDNA #ctDNA #UMIs #cancers #lymsm #breastcancer #barcoding #PrecisionMedicine #lymphoma #ICGC #PCAWG #CAPP #livercancer #BCL6 #TCGA #APOBEC #pancreaticcancer #MYC #bcsm #lymphomas #melanoma #MRD #sequencing #BCL2

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