Discover and read the best of Twitter Threads about #arcturus

Most recents (24)

„Der technische Unterausschuss der WHO für die Auswahl von Impfstämmen hat sich letzte Woche auf eine Empfehlung geeinigt, den ursprünglichen #SARSCoV2-Wildtyp-Stamm zu entfernen. Ich bin ziemlich sicher, dass diese Empfehlung den Weg zum VRBPAC finden wird.“

#COVID19 #Corona
➡️ Unsere Ergebnisse deuten darauf hin, dass der Ahnenstamm im derzeitigen bivalenten #COVID19-Impfstoff die Ursache für eine tiefe immunologische Prägung ist. Seine Entfernung aus künftigen Impfstoffzusammensetzungen wird daher dringend empfohlen.

biorxiv.org/content/10.110…
➡️ Unsere Ergebnisse deuten darauf hin, dass die WT-Komponente bei der Aktualisierung der COVID-19-Impfstoffe für #XBB-Linien aufgegeben werden sollte, und dass Personen, die noch nicht mit -#Omicron in Kontakt gekommen sind, zwei aktualisierte
Read 4 tweets
„Medium COVID“ in Delhi National Capital Region

➡️ 56% der Einwohner von Delhi NCR, die in den letzten 45 Tagen an #COVID19 oder einer Krankheit mit ähnlichen Symptomen erkrankt waren, leiden unter anhaltendem Husten
➡️ 22% der Befragten haben…

#MediumCovid #Corona #ARCTURUS Image
„anhaltende Atemnot und Fatigue“
- Jeweils 11 % haben „anhaltende Erkältung, Gelenkschmerzen, Brustentzündung und Stottern“.

An der Umfrage nahmen über 10.000 Einwohner von Delhi, Noida, Ghaziabad, Gurugram und Faridabad teil. 64 % der Befragten waren Männer, 36 % waren Frauen.
Die Umfrage wurde über die LocalCircles-Plattform durchgeführt, und alle Teilnehmer waren validierte Bürger, die bei LocalCircles registriert sein mussten, um an dieser Umfrage teilnehmen zu können.

Auf LocalCircles berichten Menschen von den anhaltenden Beschwerden, unter denen Image
Read 11 tweets
Singer Lizzo struck down by virus after performing a few days ago at the Met gala and now has to cancel shows: her account has been put on lockdown since going public about her illness after super spreader show:

#xbb116 #sars3 #Arcturus #Covid19

h/t @anordinarygirl Image
Looks like she was the victim of a GBD pile on to me: welcome to our world Lizzo: Image
Image
Read 16 tweets
Someone on just asked me if I'd read the reports about how masks don't work. My answer:
"You mean the crackpot anti-mask 'theories' designed to dupe people into believing masks don't work so we could get to this point in history when the World Health Organisation 1/
(WHO) openly collaborates with the profiteers of the Capitalist system to officially declare a Level 3 biohazard pandemic over at the expense of millions more future deaths and the crippling of people's (including children) health for the rest of their lives? 2/
Yes, I've read them. After I finished reading them I put them where they belong - in the blazing fire of humanity's fury." 3/3
#WearAMask
#COVIDisAirborne
#Arcturus
Read 3 tweets
China has brought back testing centers as well: all around Asia (ie those closest to India, the home of #XBB116 #SARS3 #Arcturus #COVID19 we see increasing signs to control the virus: they are only a few weeks ahead of us in terms of spreads and are currently being hammered
I get serious Jan 2020 vibes from all this:
Despite the fact we see so many countries taking some form of action in Asia, with the Indian PM himself decalring that 'covid is far from over' months ago now and announcing a 5 point strategy to tackle the new strain: I see nothing in the west at all

Read 10 tweets
#Arcturus is already in the UK at lower levels. We can all play our part to prevent a bigger wave. #WearAMask #N95 Open windows. Please watch this video from WHO ‘hundreds of millions’ of people will need long term care. Why isn’t this on the news @BBCNews the Public need to know
Risk increases with each reinfection as you can see from the graph below. The more times you catch COVID the greater your risk.
Read 4 tweets
BREAKING🔔 The 19th paper from G2P-Japan🇯🇵 is out at Lancet Infectious Diseases @TheLancetInfDis . We elucidated the virological characteristics of new SARS-CoV-2 variant of interest, XBB.1.16 (aka #Arcturus) Please RT🔥 1/
thelancet.com/journals/lanin…
XBB.1.16 = XBB.1 + #F486P, #E180V, and #T478K in spike.
cf. XBB.1.5 = XBB.1 + #F486P in spike (i.e., XBB.1.16 = XBB.1.5 + #E180V and #T478K in spike). 2/ Image
A phylogenetic tree shows that XBB.1.16 is a descendant of XBB.1, not of XBB.1.5. 3/ Image
Read 12 tweets
#SARS3 #Covid #XBB116 #Arcturus is currently at just under 2% of cases based on sampling, so we're really at the start of this thing in the UK: Image
Breaking the UK up by nation we see the areas are all roughly the same prevalence: with Wales having the least Image
However, perhaps somewhat unexpectedly according to the data, US is well ahead of the UK, WITH A 5X increase in prevelence of nearly 10% of cases currently: that's very strange and somehwat makes me very much question the UK's data on this Image
Read 4 tweets
NEW Study from the hard-hit Maharashtra area of India shows BRUTAL: #SARS3 #Covid #XBB116 #Arcturus strain has a fatality rate of 1 in 40 with a staggering 1 in 3 needing oxygen, and nearly 30% being hospitalised with the new strain: Image
Finally we have something resembling some form of actual data from India about this strain: and it's not pretty:

'Among the XBB.1.16* cases, 91.7% were vaccinated with at least one dose of vaccine against COVID-19. While 74.3% of XBB.1.16* ...
..cases were home-isolated; 25.7% needed hospitalization/institutional quarantine, of these, 33.8% needed oxygen therapy. Out of 276 XBB.1.16* cases, seven (2.5%) cases succumbed to the disease.'

medrxiv.org/content/10.110…
Read 18 tweets
WATCH: explained here is how the new breakthrough PL-M drug works against any strain of the virus and that means it's going to work on the new #SARS3 #arcturus #xbb116 India strain that is frankly shaping up to be BRUTAL:

Galectin inhibitors are a brand new type of antiviral: they work by attaching to the galectin fold of the virus: a part of the virus which will not mutate unlike the spike, which is endlessly mutating, and the target of the vaccines: Image
Read 13 tweets
Some more info on XBB.2.3. Aka #Acrux

➡️ XBB.2.3 has 4 defining mutations:

-Spike mutations: S:D253G & S:P521S
-ORF mutations: ORF1a:G2091S & ORF7a:A13V
-Beyond XBB.2, #Acrux XBB.2.3 has the Spike P521S & S486P mutations 1/

H/T: @T_Brautigan
➡️ Acrux XBB.2.3 was first spotted in India (Karnataka) & then in the USA—origin is somewhat unclear.

Here is the animated map by @Mike_Honey_ showing the spread of the XBB.2.3.* "Acrux" variant around the world. 2/

➡️ Singapore (26%) and India (22%) are still the hotspots.

Spain (11%) and Australia (8%) are also showing recent growth.

Spotted in many other countries including Japan, South Korea, China, the UK & the US. 3/ Image
Read 7 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

56.2% XBB.1.5
6.1% XBB.1.9.1
4.5% XBB.1.16
2.2% XBB.1.5.1
2.1% XBB.1.9.2
1.4% XBB.1.5.13
1.4% XBB.1.5.15
1.4% XBB.1.5.17

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 05/01/23

1/n Image
#COVID19 #VariantDashboard - #USA
[without sequences from "Airport Surveillance"]

Top lineages (#15DayTrends):

XBB.1.5 (61.7%)
XBB.1.9.1 (5.5%)
XBB.1.16 (2.4%)
XBB.1.5.1 (2.3%)
XBB.1.5.13 (1.6%)
XBB.1.5.17 (1.6%)
XBB.1.9.2 (1.6%)
XBB.1.5.15 (1.3%)
FD.2 (1%)

2/n Image
Airport sequences constitute ~12.4% of sequences with sample collection dates in the last 15 days (#15DayTrends)

Its going to be a three way race to outcompete XBB.1.5*: XBB.1.9* vs XBB.1.16* vs XBB.2.3*

As of now, XBB.1.16* family looks to over take everything else!

3/n Image
Read 17 tweets
I'm not aware of the OP's location, but I think it's the UK: in order to get paramedics out in the UK you basically have to be dead so she ain't kidding — it's severe
Read 6 tweets
As the new Indian #SARS3 #Arcturus #XBB116 strain takes off across the world, more and more are reporting horrific Covid eyes:

Studies show that Covid eyes contain infectious virus capable of infecting others: the eyes, do indeed, have it: twitter.com/i/web/status/1… Image
'We found that ocular fluids from SARS-CoV-2–infected patients may contain infectious virus, and hence may be a potential source of infection'
acpjournals.org/doi/10.7326/M2…
Interestingly, the CT value of the infected shows a lower (and therefore more infectious) value on day 13 than from the nose itself:

Further, on day 27 after seeming to go up and become less infectious,they then go back down implying they are more infectious.. Image
Read 15 tweets
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 8,182 (circulating in 43 countries)

Tracker:public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance

Updated:05/01/23 Image
Tracker now includes all the designated XBB.1.16* sub-lineages

Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally Image
Read 4 tweets
WARNING ABOUT #XBB116 #SARS3 #Arcturus COVID EYES FROM TIKTOKER WHO ENDED UP HAVING 'bleeding eyes' which Drs had to 'rip out of my face' after 'mild' cold-like symptoms to begin with...

h/t @AprilDalaman twitter.com/i/web/status/1… Image
His horrific story is explained here: it all started with a 'severe cold' 3 weeks ago: which apparently resolved after a week...however, virus had already spread to the eyes and infected them: Image
It just got worse and worse and to the point where his eyes were swollen shut as the virus continued to replicate in the eyes: which contain high levels of ACE2 receptors that the virus uses to attach and replicate in: Image
Read 4 tweets
It's likely that you'll be hearing more about another XBB descendant lineage, XBB.2.3*, alongside XBB.1.5 (Kraken), XBB.1.9.1 (Hyperion), and XBB.1.16 (Arcturus).

To aid communication, we're nicknaming XBB.2.3* "Acrux" (after the star en.wikipedia.org/wiki/Acrux).
This is in keeping with the new nicknaming system that uses astronomical names and includes information about the lineage (starts with A-H = BA.2 lineage) and recombinant ancestry (has an R in the name = recombinant descendant).

whn.global/common-names-f…
It's easy to track variant info thanks to amazing tools by folks like @Mike_Honey_, @RajlabN, and @nextstrain.

public.tableau.com/app/profile/ra…
Read 10 tweets
Interestng that #Arcturus #Covid is trending in the UK: for those only joining the story now: bear in mind that the strain, which originated in india is considered so dire that even their far-right PM Modi brought back masks and said 'covid is far from over' Image
Read 29 tweets
🎉CoVariants.org Update!🎉

23B (XBB.1.16) is now available on CoVariants! It's visible as part of Per Country & Per Variant plots, on the shared mutation page - and of course, has a page of its own.

1/10

#XBB116 #23B #Arcturus
📷 Image
This is in line with the recent addition of 23B (XBB.1.16) as a @nextstrain clade - read more on that below 👇🏻!

2/10

As I covered earlier, 23B (XBB.1.16) is descended from the recombinant 22F (XBB) variant, with some additional mutations. You can read more about how it evolved & acquired those mutations below 👇🏻.

3/10

Read 10 tweets
XBB.1.16 #Arcturus Covid surge in India: How it is affecting young children & infants.

Here are the key findings based on our study of 25 children from April 4-16’ 23:

1-Current outbreak is causing a mild febrile illness
2-Total duration of illness is only 1-3 days. 1/
3-Young infants are disproportionately more affected than older children.

4-The youngest infant was 13 day old neonate!

5-infants below one year had a significantly higher positivity rate than older children (40.38% versus 10.5%, p=000816). 2/ Image
6-Unlike the previous BA.2 Omicron wave, respiratory symptoms are predominating in young infants

7-Cycle threshold values for nucleocapsid and ORFlab genes on positive RT-PCR vary from 18 to 23. 3/
Read 6 tweets
Dark LOL at the latest efforts to spin this as Severe Allergy Respiratory Syndrome season.
Read 4 tweets
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 4,837 (circulating in 37 countries)

Tracker: public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance
Updated:04/20/23 Image
New entrant: #Bulgaria Image
Tracking #SARSCoV2 lineage XBB.1.16.1 over time - Globally

Total Sequences : 1003

racker: public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance

Updated: 04/20/23 Image
Read 4 tweets
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 4,200 (circulating in 34 countries)

Tracker: public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance

Updated: 04/17/23 Image
Tracking #SARSCOV2 Lineage XBB.1.16.1* (XBB.1.16 + Spike T547I) - Globally

Total Sequences: 887 Image
Tracking #SARSCOV2 Lineage XBB.1.16* in #India

Total Sequences: 2,519

Note: Recent epi-weeks are incomplete Image
Read 4 tweets
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 3,576 (circulating in 33 countries)

Tracker: public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance

Updated: 04/15/23 Image
Tracking #SARSCOV2 Lineage XBB.1.16.1* (XBB.1.16 + Spike T547I) - Globally

Total Sequences: 749 Image
Tracking #SARSCOV2 Lineage XBB.1.16* in #India

Total Sequences: 2,252

Note: Recent epi-weeks are incomplete Image
Read 4 tweets

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