Discover and read the best of Twitter Threads about #aspenkidney
Most recents (9)
Next up Alkesh Jani to talk about literature review in transplant #AspenKidney 
Wait list is stable and transplants are going up to more deceased donors. #AspenKidney
Kidneys and Patients are doing better over time #AspenKidney
Next up is @doc_faubel again for a lit review in AKI. She starts out saying that she will not be able to go over all 68,000 articles in pubmed on the topic. Also nice shout out to #NephJC
#AspenKidney
#AspenKidney
Dose of dialysis Ronco CRRT 20 ml/kg/hr vs 35 vs 45 from 2000 #AspenKidney
ATN 20 ml/kg/hr vs 35 CRRT or 3 day/week or 6 d/wk with IHD
She says this is one of the greatest RCT ever done in nephrology.
The study was negative with a bunch of negative outcomes with intensive dialysis #AspenKidney
She says this is one of the greatest RCT ever done in nephrology.
The study was negative with a bunch of negative outcomes with intensive dialysis #AspenKidney
Next up is Joshua Thurman with a lot review of GN
first study is BLISS-LN. Mentions that 2 years of infusions in 448 patients is a big lift. Points out they changed the outcome (probably listens to @NephJC_Podcast (nephjc.com/freelyfiltered…) #AspenKidney
Her is underwelmed with the magnitude of the effect size. He is not sure how to use it. #AspenKidney
Her original title was “Beyond the ouch hypothesis, a new paradigm to explain the harm in AKI.” #AspenKidney
Mortality in ICU:
No AKI, No HD 5%
ESRD HD 11%
AKI no HD 23%
AKI with HD 58%
Standardized for APACHE 2 scores
#AspenKidney
No AKI, No HD 5%
ESRD HD 11%
AKI no HD 23%
AKI with HD 58%
Standardized for APACHE 2 scores
#AspenKidney
Injured kidneys may be lashing out, releasing substances that cause systemic effects contributing to mortality. These substances are unique from substances that accumulate with zero GFR.
#AspenKidney
#AspenKidney
Next up Mats Wahlstrom on The Next Generation of Dialysis. Former CEO of Fresenius and Gambro. #AspenKidney
We are seeing a major investment in home therapies. Credits government initiatives. We are currently at 2% home hemo and 10% PD. #AspenKidney
He credits NextStage as putting home hemo back on the map. Small. Portable. Easy to use. Online dialysat4e production. Major driver of success: Capturing commercial payers! #AspenKidney
#AspenKidney Preservative management of CKD: life sustaining conservative management, delay dialysis by pharmacological and modifying diet and lifestyle.
He says even though we closed the book (MDRD study) on low protein diet 30 years ago we are reopening the book.
low protein 0.6 to 0.8 g/kg
Very low protein diet 0.3 g/kg
#AspenKidney
low protein 0.6 to 0.8 g/kg
Very low protein diet 0.3 g/kg
#AspenKidney
Next up Isaac Teitelbaum on Delivering High Quality Peritoneal Dialysis: What Really Matters? #AspenKidney
Teitelbaum measures Kt/V and then ignores it. He starts by focusing on the poor quality of V in the equation. 95% CI will range Kt/V from 1.44 to 1.94 (and that is using bioimpedence) #AspenKidney
If you use anthropomorphic formulas (which we all do) will be off ±20% Think Kt/V ranging from 1.44 to 2.06 #AspenKidney
Next up at #AspenKidney is Jessica Kendrick fellowship PD to talk about CKD and Acid-Base Disorders
Metabolic acidosis, defined as HCO3 < 22, is found in 20% of stage 4 CKD. #AspenKidney
Ammonia is responsible for most of the renal adaption to metabolic acidosis. Requires proximal tubule function. Becomes problematic as GFR falls below 45. #AspenKidney
Kicking off the 47th Annual Course on Renal Disease and Electrolyte Disorders (I am declaring the hashtag to be #AspenKidney) is @kamkalantar with a talk on incremental dialysis.
Recognizing that we are 2 years away from 50 year mark from @dick_nixon expanding chronic dialysis to all Americans. 50 Years! Wow. #AspenKidney
Starting dialysis is marked by high mortality, high cost. #AspenKidney
