Discover and read the best of Twitter Threads about #aspirin

Most recents (16)

1) Welcome to an #accredited #tweetorial on a unique emerging (in Ph3 now) option for specifically reversing the #antiplatelet effects of #ticagrelor: it's #bentracimab. Expert faculty is antithrombotic agent reversal guru @md_pollack of @UMMCnews, working to create #AHealthierMS
2) This program is intended for #healthcare professionals and is supported by an educational grant from PhaseBio Pharmaceuticals. Faculty disclosures are listed at cardiometabolic-ce.com/disclosures/, and prior programs are available for 🆓CE/#CME credit at cardiometabolic-ce.com.
3) It is an unfortunate fact of life that one cannot prescribe #anticoagulant or #antiplatelet (together, #antithrombotic) therapy without increasing a patient's #bleedingrisk. That is why it should be an individualized risk:benefit decision, ideally . . .
Read 51 tweets
Don’t miss a new accredited #tweetorial launching TOMORROW here on @cardiomet_CE. #Interventional #cardiologist, #researcher, & #SoMe education leader @DLBHATTMD will be talking all about #aspirin, its role in #cardiovascular wellness & prevention, and new approaches to . . .
1) Welcome to an #accredited #tweetorial on the foundational role of #aspirin in #cardiovascular care. There are new approaches to #aspirin formulation & dosing. This program is accredited for 0.50h CE/#CME. I am @DLBHATTMD. #FOAMed #cardiotwitter #medtwitter Image
Read 49 tweets
Don’t miss a new accredited #tweetorial launching TOMORROW here on @cardiomet_CE. #Cardiologist, #SoMe education advocate, and true #Renaissance man @CMichaelGibson will be discussing a novel #aspirin prep that has PK/PD like plain #ASA . . .
. . . but a different site of absorption--with greater predictability than ECASA. DON'T MISS IT!! @DLBHATTMD @cpcannon @AnnMarieNavar @DrM_ODonoghue @DrMarthaGulati @practicalcardio @GuyattGH @DrMauricioCohen @SVRaoMD @ASPCardio @PlateletDoc @stephanamayer #FOAMed #CardioTwitter
1) Welcome to a #tweetorial where we’ll explore how changing the formulation of #aspirin & where it's absorbed in the GI tract can ⬇️the risk of acute GI injury, but still maintain predictable absorption. This program is accredited for 0.50h CE/#CME. I am @CMichaelGibson. #FOAMed Image
Read 42 tweets
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses. Image
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011 Image
The influence of #HLA genotype on the severity of #COVID19 infection
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic. Image
Read 199 tweets
10 common causes of heavy menstrual flow you should know

1. Fibroids
2. Pelvic infections
3. Some drugs
4. Polyps
5. IUCDs
6. Endometriosis
7. Adenomyosis
8. Blood clotting problems
9. Cancers of the womb or cervix
10. Thyroid disease

A thread 🧵

{Share to who needs this!}
If a woman loses more than 80ml of blood in one period, the bleeding is heavy. Heavy periods usually often come with blood clots.

Although methods of quantifying the exact amount of blood loss are not usually accurate, most women know when their period is heavy.
Nearly 20% of women over 30 years have #fibroids.They are of different types & may cause heavy menstrual bleeding.

Treatment of fibroids depends on the many factors so see your doctor.
Read 15 tweets
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action. jjcouey.medium.com/5-concerns-abo…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus. Image
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component. Image
Read 213 tweets
#ACC21 late-breakers🧵
1/Antiplatelets: Let's start with #aspirin
❌ADAPTABLE :Aspirin 325 mg vs 81 mg in ASCVD pts
No difference in death/ MI/ stroke/major bleeding
💎pragmatic trial: EHR-identified pts
💎significant dose switching in 325 mg group
nejm.org/doi/full/10.10…
✅Host Exam: Aspirin vs Clopidogrel in chronic Maintenance monotherapy after #PCI w/ DES
#Clopidogrel monotherapy reduced composite of death, non-fatal MI, stroke, ACS re-admission, BARC >=3 bleeding, compared to #aspirin monotherapy.
❓East Asian paradox
thelancet.com/journals/lance…
✅TALOS- AMI: De-escalation ✅
In pts w/ no major events in 1st month after index PCI, de-escalation of DAPT from #ticagrelor to #clopidogrel is superior to tica-only DAPT in terms of net clinical benefit, with
⬇️decreased bleeding 🩸risk
- no increase in ischaemic risk
#ACC21
Read 16 tweets
Reducing #COVID19 #Airborne #Transmission Risks on #PublicTransportation Buses
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%. Image
🔝#SARSCoV2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies. Image
High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others Image
Read 236 tweets
⚠️#Ocular #MRI Findings in Patients with Severe #COVID19: A Retrospective Multicenter Observational Study
» doi.org/10.1148/radiol…
All patients had nodules in the macular region, 8/9 (89%) had bilateral nodules, 2/9 (22%) had nodules outside the macular region. Screening needed. Image
⚠️🔝New-Onset #IgG #Autoantibodies in Hospitalized Patients with #COVID19
» doi.org/10.1101/2021.0…
An international team of researchers studying COVID-19 has made a startling and pivotal discovery: The virus appears to cause the body to make weapons to attack its own tissues. Image
⚠️🔝Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance
» academic.oup.com/eurheartj/adva…
Damage to the heart found in more than half of #COVID19 patients discharged from hospital who show raised levels of troponin. Image
Read 235 tweets
Very important and high-yield #AIBD2020 session with @UmaMahadevanIBD on #IBD in #pregnancy! 🤰🔥💩👶
⬇️⬇️⬇️

@IBDConference #GITwitter #GI #OBGYNtwitter #OBGYN
Management of a healthy pregnancy begins... before pregnancy!

#AIBD2020 @IBDConference @UmaMahadevanIBD #IBD
Start planning early!

Want 3 months of steroid-free remission before conception.

#AIBD2020 @IBDConference @UmaMahadevanIBD #IBD
Read 23 tweets
With the .@NIAIDNews #ACCT1 trial final report published on 05 Nov 2020 and the .@WHO's #SolidarityTrial Preliminary report published on 02 December 2020, thought it would be good to take another look at both trials and find ways forward for the patients we are dealing with today
Motivated by a patient I am dealing with who will survive very severe #COVID19 in the setting of transplant, but her father, who was hospitalized earlier than her with moderate COVID, was left to progress and died before her discharge, given #remdesivir only after going on #BiPAP
Here is the link to the prior analysis and I think the new publications give some interesting details which will follow

Read 39 tweets
9 common causes of heavy menstrual bleeding everyone should know

1. Fibroids
2. Pelvic infections
3. Drugs
4. Polyps
5. IUCDs
6. Endometriosis
7. Blood clotting problems
8. Cancers of the womb or cervix
9. Thyroid disease

A thread 🧵

{Share for awareness!}
If a woman loses more than 80ml of blood in one period, the bleeding is heavy.

Although methods of quantifying the exact amount of blood loss are not usually accurate, most women know when their period is heavy & heavy usually often come with blood clots.
1
Nearly 20% of women over 30 years have #fibroids.

They are of different types & may cause heavy menstrual bleeding.

Treatment depends on the many factors. So see your doctor. Source: National Health Service, Fibroids, United Kingdom,
Read 14 tweets
Good Day 🌎! Are you ready for one of Gods🌿to be Federally Legalized? I have stood strong on this since #DJT announced he would run in 2015. Follow along for my thoughts and leave a comment below. Please retweet and lets help those who need it most. #WWG1WGA
2) Starting off we know the issues with his brother and #Alcohol which for most would lead them to believe he was completely against any and all substances. However I am lead to believe the exact opposite.
3) #Drugs and #Alcohol both are known to have horrible side effects that contribute to many of the horrible #sickness and #disease we know today. We have all long known the power of this 🌿. This leads me to a Poll, Lets keep you engaged!
Read 18 tweets
THREAD: Split This! A TI tweetorial on pill splitting

1/ Split this! Pill splitting (dividing tablets into smaller doses)

Practical tips to help patients + their families make the most of their medications during the #COVID19 pandemic

#medication #pillsplitting #TIEvidence Image
2/ Split this! PILL SPLITTING can safely extend medication supplies longer, saving 💰💰 and 🚗 to the pharmacy

Most pharmacies carry pill splitters for as little as $5 😀

Consumer reports review: tinyurl.com/ycstbx2t

#medication #pillsplitting #TIEvidence
3/ Split This! #CHOLESTEROL-LOWERING DRUGS

Do you take 20mg of atorvastatin every day? Ask for 40mg tablets and split them, saving 💰💰 and 🚍 to the pharmacy

#medication #pillsplitting #TIEvidence #cholesterol Image
Read 9 tweets
Study warns against combined use of oral #anticoagulants , #antiplatelet therapy for #AFib 1️⃣

#GARFIELD-AF registry

escardio.org/The-ESC/Press-…
2️⃣ Currently, do you stop #aspirin w #NOAC #DOAC for #AFIB in pts w previous history of stent (>1yr prior) for non-ACS CAD ? (Yes- I know it should be a less and less common scenario)
3️⃣ Currently, do you stop #aspirin w #NOAC #DOAC for #AFIB in pts w previous history of CAD ( #STEMI / #NSTE-ACS >1year prior) ?
Read 3 tweets
@ShawnMcGuirk @CFAMMcan @mcgillu @santecannabis @trinafraser #ACMPR highlights #WeedLikeToKnow :
- limit of <30-day supply or 150g
- LP delivery by mail only, no retail point of sale
- medical doc lasts 1 year
- storage limit (to be removed soon with #CannabisAct )
- Soon, might be able to transfer from one licensed producer to another
@ShawnMcGuirk @CFAMMcan @mcgillu @santecannabis @trinafraser #CannabisAct Bill #C45 removes #cannabis from #cdsa, separate act will be created for regulation of cannabis
- Can grow up to 4 plants (debated) in dwelling
- legal limit up to 30g in public
- anticipate royal ascent by end of June, coming into force Sept/Oct 2018
#WeedLikeToKnow
@ShawnMcGuirk @CFAMMcan @mcgillu @santecannabis @trinafraser There is still reluctance in prescribing #MedicalCannabis, and there is lack of point of sale (still will have to be by mail), excise tax and HST/GST upcoming, lack of drug plan coverage.
#WeedLikeToKnow #SPEforum
Read 21 tweets

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