Discover and read the best of Twitter Threads about #astrocytes

Most recents (5)

1/🧵 Long COVID Brain Science: 🧠

For ~100M suffering 🌎, let’s use data to combat myths & #Misinformation

COVID is biologically dangerous long after virus is gone

#LongCOVID affects our….

📍Olfactory & Limbic Systems
📍 Interferon Autoimmunity
📍PET scans
📍Astrocytes

How? Image
2/ First, Epidemiological comparisons…

FLU vs. COVID

Survivors of viral infxns like #Flu don’t complain of 200 long-term symptoms & ~90% ongoing mood disorders.

#LongCOVID pts do.

Flu kills 0.5M/year vs COVID has killed 10X that (5M) in just 2 years.

bit.ly/3mJTBK4
3/ Consider this:

A study of 150k COVID survivors, hospitalized & not.

COVID survivors had 10-15X ‼️higher risk of considering #suicide at 1 year than 11M control patients.

This is horrifying, yet people still deny #LongCOVID’s importance.

WHY?

bit.ly/3HnHZpB ImageImageImage
Read 27 tweets
The receptors involved in SARS-CoV-2 infection are co-expressed in the cells of the NVU, especially in astrocytes and microglial cells. These receptors are functionally active as exposure of endothelial cells to the SARS CoV-2 S1 protein subunit ..
#HIV
#ACE2
#brain
altered the expression pattern of tight junction proteins, such as claudin-5 and ZO-1. Additionally, HIV-1 infection upregulated ACE2 and TMPRSS2 expression in brain astrocytes and microglia cells.
#astrocytes
#microglia
#brain
SC2 in BBB mechanism. Image
Read 10 tweets
Ooof interesting! This team found Ljungan #virus (LV) antigens in autopsied #brain tissue from the hippocampus region of 18 #Alzheimer’s brains. No LV antigen was identified in any of their 11 age-matched control brains: ncbi.nlm.nih.gov/pmc/articles/P…
2/ The LV virus antibodies reacted with #neurons and #astrocytes and also showed distinct positive reaction in the #amyloid/neuritic plaques. The team thinks the findings indicate LV #virus may persist in the Alzheimer’s brain
3/ Here’s an image from one of the #Alzheimer’s brains. The red stain visualizes presence of LV viral antigen in neurons, astrocytes + #glial cells. In Panel C, an amyloid/neuritic plaque is shown staining positive in the glial compartment + in dystrophic neurites Image
Read 4 tweets
@AchucarroGlia organises an innovative concept of advanced training course for researchers focused or willing to work in the vibrant field of glial cells #GLIA #gliaSchool2020 🧠 🔍
Thread 👇
📌 From June 23 to 25, 2020 in Bilbao 🌎
@VisitBasqueCtry #gliaSchool2020
This School fosters close interactions between speakers and attendees during three intense days.
With 🧬Practical 🧪 demonstrations of 🔬techniques and 📙 Brainstorming sessions. #gliaSchool2020
Read 10 tweets
#Euroglia 2019 in #Porto (PT) has just published the Meeting Program.
Very much looking forward to be there! #GliaMeeting #NetworkGlia #glia
glia2019.eu/_medien/_conte…
New in this edition:
To promote interactions between speakers and attendants, the program includes a session called “meet the speakers”. The sessions will take place during the lunch breaks from Thursday to Saturday; glia2019.eu/?s=meet-the-sp…
What about the Posters in #Euroglia 2019 ??
Read 23 tweets

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