Discover and read the best of Twitter Threads about #asymptomatic

Most recents (24)

Welcome to #Ontario !
#YoursToDiscover - ONLY if you are quadruple vaccinated, wear 3 N-95 masks & shower 3 times daily in 100% alcohol.

#APlaceToGrow - ONLY variants that ignore our #shortcutvaccine !

#FlawedData - because "transparency" was never a license plate slogan.

1/..
#FlawedDataUpdate:
We put out some pretty little graphs for you!

They give the ILLUSION of #transparency - but we're NOT going to tell you which group the has more UNvaccinated vs Vaccinated - NOR how many shots they've had. NOPE!

Rumors of testing bias? PLS don't ask!

2/
We are quite pleased that most of #Ontario & the media actually thought that adding the numbers in these graphs gave you correct totals.

We were quite tickled that many of you calculated rates using these graphs.

973 are missing from the 1st graph!
150 from the 2nd!

3/...
Read 17 tweets
More info on the @CancerPrev_KCL & @CR_UK-run NHS-Galleri™ #screening trial:

kcl.ac.uk/news/kings-lea…

cancerresearchuk.org/about-cancer/c…

Worth noting you can't #volunteer for this trial, but if you are 50-77 & haven't been diagnosed with cancer in the past 3 years, you may be #invited... Image
The NHS-Galleri™ #screening trial is a proper #RCT, which means half of the 140,000 participants WON'T be tested (certainly not in the initial phase) and NONE will be told whether they have been #tested or not.

Of course if the test indicates *possible* markers for #cancer... Image
...then you will be contacted by the trial nurse by phone, and will be referred to an NHS hospital for further tests.

So every participant in the NHS-Galleri™ #screening trial should still attend standard screening & should contact their GP if they notice any unusual symptoms: Image
Read 5 tweets
#WeekendLecture
#CarotidArteryDisease #CAD

#CAD causes ~ 10-20% of #strokes
Atherosclerosis occurs most frequently at carotid #bifurcation, an area of low vessel-wall shear stress and oscillatory/turbulent blood flow

Welcome to this mini review!
#WeekendLecture
#CAD
Endothelial dysfunction
⬇️
Inflammatory response to Lp retention in arterial wall
⬇️
Accelerated accumulation of Lp in subendothelial matrix
⬇️
Macrophages
⬇️
VSCM migrate/proliferate to fibroblast-like cells👉 production of EC matrix
atm.amegroups.com/article/view/7…
#WeekendLecture
#CAD
Stroke Mechanisms
#artery_to_artery embolization: retinal (amaurosis fugax) or cerebral circulation
#thrombosis in situ
#Flow reduction in high grade stenosis: #watershed infarcts, repetitive and brief TIAs (ie limb shaking)

nejm.org/doi/full/10.10…
Read 12 tweets
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses. Image
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011 Image
The influence of #HLA genotype on the severity of #COVID19 infection
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic. Image
Read 199 tweets
Ultimate victims of media induced fear & politically correct #posturing will be our #children. "hygiene hypothesis: "when exposure to parasites, bacteria, & #viruses is limited early in life, children face a greater chance of [] allergies, asthma, & other #autoimmune diseases..." Image
Dec 10, 2020, Nature: "'#Children are very much adapted to respond — & very well equipped to respond — to new #viruses,' [] even when they are infected w/ #SARSCoV2, children are most likely to experience #mild or #asymptomatic illness." Image
"These children’s #immune systems see the #virus & mounts this really quick & effective immune response that shuts it down, before it has a chance to replicate to the point that it comes up positive on the swab diagnostic test",

Natural #Immunity is not a conspiracy theory.
Read 12 tweets
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action. jjcouey.medium.com/5-concerns-abo…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus. Image
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component. Image
Read 213 tweets
1/x Quoting/translated

„The ORF report is the ONE.
One just HAS to let the last sentence melt in one’s mouth:

"Infections WITHOUT symptoms (ie #ASYMPTOMATIC) are NOT counted"

[Thus, are] vaccinated people better people in several ways [?]“

Added:
Huh?
2/x To repeat:

„SARSCOV2 Infektionen OHNE Erkrankungs-symptome werden NICHT mitgezählt“

Translated,

"[Amongst fully vaccinated people], SARSCOV2 Infections WITHOUT symptoms of illness (ie #ASYMPTOMATIC) are NOT counted [!]“
3/x We‘ve been saying that for > 1 YEAR that #asymptomatic people who test PCR positive should NOT be counted NOR reported as „CASES“ as they do not contribute to INFECTIOUS OUTBREAKS

Only symptomatics and presymptomatics may contribute to infectious outbreaks (see Pinned Tweet)
Read 8 tweets
💈One Year On. Our scrapbook.

Kids do get #COVID19
Kids can be #Asymptomatic or #Atypical.
Kids can have a mild infection, or get #PIMS
Kids can get #LongCovid

2000 kids NOT yet better.
Families disbelieved.

⚠️Contains graphic images.

longcovidkids.org #MothersDay
The numbers of children with #LongCovid are rising with every #COVID19 infection.

⚠️1 in 8 primary age children will get Long Covid
⚠️1 in 7 secondary age children will get Long Covid.

It appears to makes no difference if a child has a pre-existing condition or not.
Tragically children can die.

Thankfully the numbers are low compared with adults.

Every family that has lost a child will be devastated, the fact the numbers are low will have no bearing on their grief.

longcovidkids.org

#LongCovidKids #MakeSchoolsSafe
Read 6 tweets
Reducing #COVID19 #Airborne #Transmission Risks on #PublicTransportation Buses
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%. Image
🔝#SARSCoV2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies. Image
High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others Image
Read 236 tweets
⚠️#Ocular #MRI Findings in Patients with Severe #COVID19: A Retrospective Multicenter Observational Study
» doi.org/10.1148/radiol…
All patients had nodules in the macular region, 8/9 (89%) had bilateral nodules, 2/9 (22%) had nodules outside the macular region. Screening needed. Image
⚠️🔝New-Onset #IgG #Autoantibodies in Hospitalized Patients with #COVID19
» doi.org/10.1101/2021.0…
An international team of researchers studying COVID-19 has made a startling and pivotal discovery: The virus appears to cause the body to make weapons to attack its own tissues. Image
⚠️🔝Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance
» academic.oup.com/eurheartj/adva…
Damage to the heart found in more than half of #COVID19 patients discharged from hospital who show raised levels of troponin. Image
Read 235 tweets
1/3 Once >50s and clinically vulnerable people have had #Covid19 #vaccine, the tradeoff of benefits and #harms for #TestAndTrace and #asymptomatic testing in particular changes rapidly. My take at @bmj_latest #CovidUnknowns seminar yesterday
2/3 Big issue - when #hospitalisation #deaths low and the vulnerable protected, why would we ask #children #parents #essentialworkers and other non-Zoomocrats to #SelfIsolate, #test over and over to leave home? Listen to @bmj_latest #Covidunknowns webinar
3/3 Will we really ask the groups already most affected by #economic and #mentalhealth impact of #Covid19 to #SelfIsolate indefinitely when life opens up for others?
Read 4 tweets
By July of 2020, 16.8 million people in the US had #COVID19 -- and didn’t know it. Read our pre-print @medrxivpreprint 🧵👇 (1/13)

medrxiv.org/content/10.110…
We called out for volunteers that never had COVID-19 dx & got >400K. Our statisticians devised a code that was able to update daily to select donors that represented the US based off of age, sex, race, ethnicity, location, & send list to @NIAIDNews, @PittTweet, & @UABNews (2/13)
Mailed out @Neoteryx dried blood samplers to >11K folks & got >9K returned. Ran 6 ELISAs on each (full Spike & RBD IgG, IgM & IgA) & evaluated seropositivity by thresholds against pre-pandemic controls (check out @NatureComms paper on our assay) (3/13) nature.com/articles/s4146…
Read 13 tweets
#OneYearAgo a "coronavirus #genome from a case of a respiratory disease from the #Wuhan outbreak" was published on #GenBank... 🧐#SARSCoV2
#OneYearAgo "The cluster of infections had raised fears of a potential epidemic after China said last week that the virus causing it was a previously unknown type but came from the same family of viruses that caused the #SARS and #MERS epidemics".🧐
reuters.com/article/us-hea…
#OneYearAgo It was suddenly clear that the virus was travelling fast... any bell ringing?🧐#covid19
cidrap.umn.edu/news-perspecti…
Read 75 tweets
1/2 Quoting/translated,

“The theory that people WITHOUT symptoms can infect others is the basis for almost ALL #government_measures.

BUT if that does NOT exist, then it is sufficient to isolate [ONLY] people with symptoms.

Here is a close examination of the sources”
2/x ..Evidence of #Asymptomatic Infection?

Quoting/translated

“Dr. Clare #Craig, a ... #pathologist and statistics [expert], and .. Dr. Jonathan #Engler examined research.. behind the CLAIM that Covid19 can be transmitted from #asymptomatic people...”

tkp.at/2020/12/21/gib…
3/x Here is important article by @ClareCraigPath and @jengleruk

“Has Evidence of #Asymptomatic Spread of COVID-19 been Significantly Overstated?”

discussed in German in the enlightening article by Peter F Mayer @pfmayer , Publizist Science & Technology

lockdownsceptics.org/has-the-eviden…
Read 5 tweets
1/ MichaelYeadon3
🙏🏻 for sharing these thought-provoking words by @emmakennytv

Watch this 3-min film made by a teen in 🇨🇦, Liv #McNeil, on how isolation and school closures can effect children

Children are largely #asymptomatic thus #NON_infectious>>

2/2 WHY are we collectively mistreating our children if science #cannot even prove that they contribute to #infectious_outbreaks in the 1st place??

(NB 1st tweet is in my thread on #asymptomatics -18 ref’s)

More on #abuse of children #InTheNameOfVirus
👇
3/3 The thread on asymptomatics, with 18 links including articles by

@ClareCraigPath
@jengleruk
@MichaelYeadon3
Beda #Stadler

Read 4 tweets
We have to stop pretending the kids are alright.

This is their planet too.

They have a right to an education ... a future.

After all, wasn’t that what we enjoyed at their age? Wouldn’t it be selfish to not offer them the same?

@DaFeid
Children are not major transmitters:

abc.net.au/news/health/20…
Quoting

“The secondary attack rate in paediatric household contacts was LOWER than in adult household contacts”

pubmed.ncbi.nlm.nih.gov/33283240/
Read 6 tweets
2.1/x That there is #negligible risk of #asymptomatic transmission

was ALSO stated by Beda M #Stadler,
fmr director of Institute Immunology at the University of Bern, biologist and prof emeritus
and medical professional in Switzerland

backtoreason.medium.com/coronavirus-wh…

@MichaelYeadon3
3.1/x A study on infectivity of #asymptomatic SARS-CoV-2 carriers

Quoting

„Conclusion:
In summary, all the 455 contacts were excluded from SARS-CoV-2 infection and we conclude that the infectivity of some asymptomatic SARS-CoV-2 carriers might be weak“

pubmed.ncbi.nlm.nih.gov/32513410/
Read 57 tweets
Time for a BIG thread and for me to return to where i made my bones: #Covid19.

This time with a prediction that will end up hurting A Lot:

#Europe will stay in lockdown until March/April 2021. If it doesn't, the virus overwhelms hospitals and forces a lockdown anyway.

1/x (50)
First, some background, as i know many of you are new to the channel (Welcome!!) and to show i'm not "just some guy on twitter".

While you probably found me because of #silver or #Tether, I made my bones correctly predicting #Covid19 would turn pandemic.

Around January 11th 2/x
Before the Virus, i was trying to become an inventor. On the 7th of January, me and my Russian friend had just ended up with a quote of about 15k to build an app i designed - but we were broke.

The plan became for me to sell a small invention to raise capital for an alpha. 3/x
Read 50 tweets
If someone gets a positive #COVID report, he/she should report to nearest Govt. health facility or #UttarPradesh #COVID Helpline 18001805145 or National #COVID_19 Helpline 1075.
On the basis of severity of symptoms, treating doctor will assign #HomeIsolation with...
(1/5)
... conditions (mild/ #asymptomatic cases) or hospitalization in #COVID__19 health facility (moderate or severe cases). Family members & other high-risk contacts of a #COVIDー19 case, will have to undergo for 14 days home #quarantine.
(2/5)
Patient under home #isolation will stand discharged after 10 days of symptom onset & no fever for 3 days. Thereafter, the #COVID_19 case will be advised to isolate at home & self-monitor their health for further 7 days. There is no need for testing after the home...
(3/5)
Read 5 tweets
@nataliexdean @EpiEllie Ooh, yes. You should judge risk of bias in #LivingSystematicReviews as you would a standard one. @jhjelliott says, „We propose living systematic review as a contribution to evidence synthesis that combines currency with rigour“ journals.plos.org/plosmedicine/a… 1/n
@nataliexdean @EpiEllie @jhjelliott Julian Elliott really started the movement with a project in @cochranecollab community.cochrane.org/review-product… and followed up with a series in J Clin Epidemiol (pt1 here sciencedirect.com/science/articl…) 2/n
Read 6 tweets
#Plasmadonation..one of the most used term nowadays, ofcorse this arouses lots of queries in a donor's mind..

Let's see if this helps to clear the air to some extent 👍summerized in 10 points.

#covidcapsules #plasmatherapy
#covidupdates
Among the 3 categories of COVID patients (severe, moderate ,mild), plasma therapy is suggested for patients who have been moderately infected.Patients with mild condition often recover easily themselves, whereas the chances of recovery in a severely-infected patient are slim.
When one contracts an infection, especially a viral infection, their recovery depends on the production of antibodies to fight the antigen ( which in the current case, is COVID-19). These antibodies are present in the recovered person’s blood for a few weeks aftr recovery.
Read 13 tweets
First report of #COVID19 #reinfection from #India - two #asymptomatic health workers identified on routine #surveillance
academic.oup.com/cid/advance-ar…

#CSIRfightsCOVID19
#Genome sequencing of the #SARSCoV2 isolates from both the episodes suggest distinctly different virus , confirming reinfection.
Since the individuals were #asymptomatic during both episodes, and identified on regular #surveillance suggest asymptomatic #reinfections could be an under-reported entity. 2/2
Read 5 tweets
Summer 1970: a rare form of typhoid is infecting people in Edinburgh. Dr Nancy Conn, a bacteriologist at Western General, finds the source and prevents a major outbreak with detective work and sanitary towels.

A thread on one of Scotland's unsung #WomenInSTEM

#OldWeirdScotland
Typhoid was and is uncommon in Scotland. Apart from an outbreak in Aberdeen in the 60s, most cases are linked to overseas travel. The Edinburgh outbreak was different. It was mainly children who were being infected, from different parts of the city. 1/n
None of them had ever been abroad and none had any link to India, where this rare strain of the Salmonella typhi bacterium comes from. Dr Conn sat with the patients and interviewed them in detail. Many were senseless with fever. She interviewed their friends and families too. 2/n
Read 20 tweets

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