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Hey Everyone!
Wanted to do a quick thread summarizing our latest work @biorxivpreprint
We went looking for regenerative cells in mammals and stumbled onto a small, but potent, group of cells in the mouse skin -
Wanted to do a quick thread summarizing our latest work @biorxivpreprint
We went looking for regenerative cells in mammals and stumbled onto a small, but potent, group of cells in the mouse skin -
1/ Exciting work out there suggests that our tissues are heterogenous mixtures of cells from different origins, differentiation states, in different niches, etc. Related to regeneration/wound healing - some bad actors may be intrinsically fibrotic
science.sciencemag.org/content/348/62…
science.sciencemag.org/content/348/62…
2/ We hypothesized that pro-regenerative cells might retain markers that are on in embryonic progenitors or be active in regeneration-competent animals (aka #axolotl)
