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Biologists love balancing selection, but detecting it is hard! Luckily, many new methods to detect signatures of balancing selection from population-level genomic data have been developed recently, and we have a deep overview of those methods for you! 🧵
academic.oup.com/gbe/article/15…
Before diving deep into recent methods, we provide the historical relevance of balancing selection throughout the 20th century
We then explain the different signatures and timescales of balancing selection and the essence of the various methods: what genetic patterns they identify and at what timescales they can detect the signatures of balancing selection.
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