Discover and read the best of Twitter Threads about #biopsy

Most recents (12)

1) Welcome to a new #accredited #tweetorial on Clinical and Laboratory Manifestations of #DKD in #T2D: From Early Identification to Monitoring Management. Your expert author is @edgarvlermamd.
2a) This activity is supported by an independent educational grant from the Boehringer Ingelheim/Lilly Alliance and is intended for healthcare providers. It is accredited for #physicians #physicianassistants #nurses #NPs #pharmacists. Check out @cardiomet_ce for more🆓CE/#CME.
Read 45 tweets
The Webinar on "Monoclonal gammopathy and its significance for kidneys" is about to begin!
There is still time to test your knowledge by solving the @ISNeducation quiz ➡️ bit.ly/3j7U5cn
Starting now!
Webinar: "Monoclonal Gammopathy of Renal Significance - Clinical Perspective" with
@arzuvelix and Serhan Tuglular
#ISNwebinar
Welcome Dr @arzuvelix and Dr Serhan Tuglular
Webinar: "Monoclonal Gammopathy of Renal Significance -Clinical Perspective" with

#ISNwebinar
Read 44 tweets
3 things you should know about cancer of the womb

1️⃣ 1 in 90 women have a life-time risk of having it

2️⃣ It often manifests with vaginal bleeding, especially after menopause

3️⃣ You can take steps to prevent it.

A thread 🧵

{Retweet for awareness!} Image
What increased your risk of having cancer if the womb?

- Obesity
- Late menopause (after 52 years)
- High estrogen levels
- Nuliparous (not giving birth)
- Diabetes
- Drugs e.g. tamoxifen, tibolone
- Family history of womb cancer esp in your mother, sister or daughter.
Once a womb cancer is suspected, two common tests can be done to confirm it;

- Trans-vaginal #ultrasound scan: the walls of the uterus might be more than 4mm thick

- Womb tissue can be taken out (#biopsy) for histology: highly definitive if done using hysteroscopy
Read 6 tweets
1/3
The devil is in the 'detailed' #drug history #clinical
22 yr male, underweight
Teetotaler
Fatigue, appetite loss
Liver test AST 400 ALT 600
Viruses negative
Liver #biopsy 👇Severe #fatty #liver #disease, Mallory Denk++
#livertwitter #pathology #MedTwitter #MedStudentTwitter Image
2/3
The culprit 👇#Ayurveda #medicine
#Ayurvedic jam with butter, honey, milk as base given for premarital #weight gain! 3 months after stopping, liver tests normal
Consider #drug induced fatty liver in #patients. Not everyone is #metabolic #syndrome
#pseudoscience #Nash #nafld Image
3/3
Common drugs causing fatty liver
Steroids, Valproate
Inj Tetracycline
#HIV #AIDS meds NRTIs
Rare - methotrexate, chemodrugs irinotecan, 5FU, tamoxifen
Also important is Amiodarone
Herbals with #Margosa oil too
Remember #alternative meds rich in fats are important causes too.
Read 3 tweets
#ToughTxCase I am going to start an educational series for #transplant professionals/trainees on complex cases I have the privilege to see @UWHealth Patients have provided informed consent for us to discuss their condition in order to help other similar cases @uw_nephrology
#ToughTxCase #1 is the story of Tom, a 73 year old man, who received a living unrelated #kidney tx for #ESRD due to an unknown etiology. Low immunological risk, VXM (-), #CMV D+/R-, basiliximab induction, standard TAC/MPA/P maintenance Rx on Valgan prophylaxis x 6M @TxPharmD
At his 3M visit, Tom complains of #diarrhea, weight loss (4 lbs in 1 month) and poor energy. His kidney fxn is at baseline Scr 1.3 mg/dL. What is the most likely diagnosis? Please feel free to discuss! @uw_IMresidency @askrenal @Nephro_Sparks
Read 35 tweets
1/2
2017: #young #male after a #trip to Hills with '#Naturalists'. Fever and abnormal liver tests. #jaundice in a week. Long evaluations multiple places. Following up as fever of unknown origin. Father a pastor. Son denies everything, studious. #Liver #biopsy done.
#livertwitter Image
2/2
Classical #liverpath
Top:Lobular #inflammation, #Portal triaditis; Bottom: central venulitis, perivenular #cholestasis
Asks young man alone, 1hr #interrogation
Finally, S(n)ORTED OUT THE PROBLEM.
#Cocaine induced #Hepatitis
Its pays to invest in good #clinical #history
Read 3 tweets
Strange cause for #cirrhosis
Maybe very #rare #MedEd
53yrs man, voice change, recurrent headaches, male breast enlargement. Stops socialising. Has bleed one day, #endoscopy varices, #biopsy fatty liver cirrhosis
No metabolic syndrome.
MRI Brain done. #livertwitter #radio
1/3 Image
What is the diagnosis?
In patients with cirrhosis, always try to find the cause in those who present early. There is no idiopathic, no cryptogenic. Its all 'missed' cirrhosis.
2/3 #liverpath
#MedTwitter #pathology #radiology #MRI #brain #Neurology #Endocrinology #NeuroTwitter Image
#diagnosis: #fatty liver related cirrhosis due to #pituatory macro adenoma with high prolactin, high GH, low #thyroid function. #clinical examination, acromegaly features with central obesity. #Examine 1st, then investigate. #MedicalStudent #medicine #MedStudentTwitter
3/3
Read 4 tweets
1/2
10 year old #boy. Loss of weight, very high #appetite, ⬆️thirst, urination - 6 months. LFT - AST 1200, ALT 2300, ALP, Bil, INR - normal. Wilsons, autoimmune -ve. IgG - 2xULN. CTscan - massive hepatomegaley. #Liver #biopsy 👇 Rare! ❓ #livertwitter #MedTwitter Image
2/2
HbA1c is 15.2🔥Uncontrolled #diabetes with hepatic #glycogenosis, diastase treatment, glycogen disappears! [Mauriac Syndrome] 6 months intensive #nutrition & #insulin, Repeat biopsy - #normal liver!
Scary presentation in a child, but simple #treatment
#medicine #pathology
Read 3 tweets
Mind boggling case
13-year old girl
5 - 6 years on #ayurvedic treatment (shown below) for #Epilepsy. #Ayurveda promised no more #seizure.
Now jaundice, fluid in abdomen, dark pigmentation
#livertwitter #MedTwitter #MedEd #Science #ScienceMatters #pathology #MedicalStudent
1/4
#liver #biopsy
Diagnosis: severe #alcohol #hepatitis and underlying #incomplete septal #cirrhosis (rare, #hepatoportal sclerosis) - 2 diseases in one liver! #radiology
WHY DID THIS HAPPEN?
See retrieved #Ayurveda #drugs analysis results.
#pseudocience
2/4
#Chemicals & #Toxicology analysis
#alcohol content - total 26.17 % v/v
#Arsenic content - total 2461.367 mg/kg
Single highest #Herbal #medicine - Arsenic was 1982.44 mg/kg
Two #ayurvedic drugs also contained #CLONAZEPAM - a modern medicine with anti seizure property😞
#ayush
3/4
Read 4 tweets
#Ayurvedic treatment of fatty #liver – real world evidence: A #Thread
1/n
Overweight woman, early 40’s. Routine liver tests, mild enzyme abnormalities. Advised #ultrasound liver, showed grade 2 #fattyliver. GP advised vitaminE and #weightloss, review in 3mo
#livertwitter
2/n
Patient and husband doubtful. Hears fatty liver disease can lead to #cirrhosis. Seeks advice from #Ayurvedic practitioner nearby #home since #Herbal #DRUGS = safe. Assures complete #cure through #Ayurveda. Prescribes multiple #medicines, advises almost all foods restriction.
3/n
Lets look at medicines. #tablet APFIL. Packet mentions ‘for liver #diseases’. Which liver disease? There is #alcohol related, #hepatitis B/C, #NAFLD, primary biliary #cholangitis and more causes. Nine #herbs extract combo - clinical #evidence on safety and benefit ❌
Read 14 tweets
(1/3) Amazing case study in the American Journal of #Transplantation:

A kidney #transplant patient was being treated for metastatic cancer using a checkpoint inhibitor, which caused the patient's immune system to reject the kidney (...)

onlinelibrary.wiley.com/doi/abs/10.111…
(2/3) After experiencing a complete response, the patient was re-transplanted with a second kidney. This second graft was monitored for rejection using a novel #liquid #biopsy.

This is the first time, to my knowledge, a patient beat cancer and active organ rejection.
(3/3) We think liquid biopsies will fundamentally change the transplant space, allowing doctors to precisely dial #immunosuppressive medication, anticipate organ rejection, and monitor organ health, using a non-invasive approach.
Read 3 tweets
Did my fellows' curriculum lecture today, "Images in #Nephrology"
Thought of sharing the slides as a tweetorial. Goal is to present some 'classic' images that aid in kidney-related diagnoses. Not exhaustive; plan to make 2nd part as well.
#MedEd #FOAMed Not much POCUS involved!
1st question. Classic image but rarely encountered. Note the super high blood urea nitrogen and serum creatinine.
Here is the answer.....
Read 61 tweets

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