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Daniela Hermelin, MD
@HermelinMD
A 23-year-old woman w/ a history of SLE was admitted to the hospital w/ abdominal pain & headache. Purpura is seen on her chest & thighs. Hb /Hct= 8.3,28.4, PLT= 7,000, LDH = 952, Hapto = <8, Ind Bili = 1.2, Cr = 1.2 PT/INR = 1.3. 👇🏼Take a look at her peripheral smear.
⁉️Based on the initial lab results and the peripheral smear findings above, what is your differential? #PathTweetorial #Blooducation #ApheresisRounds
The findings above (evidence of hemolysis, drop in platelet count & schistocytes on the peripheral smear) point to a thrombotic microangiopathic hemolytic anemia (TMA). The classic diseases that fall under this category are #TTP & #HUS. Let's review how we manage these patients
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Related hashtags

#TPE #TMA #Blooducation #PathTweetorial #BB #TotalPlasmaVolume #TotalBloodVolume #ApheresisConsult #TTP #BloodBankResident #PLASMICScore #ApheresisNurse #ApheresisRounds #HUS #Apheresis

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