Discover and read the best of Twitter Threads about #boosted

Most recents (24)

#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

39.95% BA.2.12.1**,
26.82% BA.5^^,
12.74% BA.4^^,
6.33% BA.2,
5.56% BA.5.1^^,
4.85% unassigned &
0.78% BA.2.9

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 07/01/22
#OmicronVariantUpdates #UnitedStates 07/01/22

Top 5 lineages:
BA.2.12.1, ⬇️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.4 ⬆️ (Spike: L452R)
BA.2 ⬇️
BA.5.1 ⬆️👀 (Lineage prevalent in #Portugal)

* includes recently designated BA.2.x.y and undesignated BA.2s
BA.5*/BA.4* hotspots - #UnitedStates #15DayTrends
Read 12 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

42.18% BA.2.12.1**,
25.49% BA.5^^,
12.44% BA.4^^,
7.05% BA.2,
5.04% BA.5.1^^,
3.79% unassigned and
0.86% BA.2.9

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 6/30/22
#OmicronVariantUpdates #UnitedStates 06/30/22

Top 5 lineages:
BA.2.12.1, ⬇️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.4 ↔️ (Spike: L452R)
BA.2 ⬇️
BA.5.1 ⬆️👀 (Lineage prevalent in #Portugal)

* includes recently designated BA.2.x.y and undesignated BA.2s
BA.5*/BA.4* hotspots - #UnitedStates #15DayTrends

All eyes on #NewYork!
Read 12 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

42.63% BA.2.12.1**,
24.97% BA.5^^,
12.82% BA.4^^,
7.48% BA.2,
5.13% BA.5.1,
2.93% unassigned and
1.04% BA.2.9

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 6/29/22
#OmicronVariantUpdates #UnitedStates 06/29/22

Top 5 lineages:
BA.2.12.1, ⬇️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.4 ⬆️ (Spike: L452R)
BA.2 ⬇️
BA.5.1 ⬆️👀 (Lineage prevalent in #Portugal)

* includes recently designated BA.2.x.y and undesignated BA.2s
BA.5*/BA.4* hotspots - #UnitedStates #15DayTrends

All eyes on #NewYork!
Read 12 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

43.89% BA.2.12.1**,
23.48% BA.5^^,
12.63% BA.4^^,
7.82% BA.2,
5.22% BA.5.1^^,
2.54% unassigned and
1.18% BA.2.9

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 6/28/22 Image
#OmicronVariantUpdates #UnitedStates 06/28/22

Top 5 lineages:
BA.2.12.1, ⬇️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.4 ⬆️ (Spike: L452R)
BA.2 ⬇️
BA.5.1 ⬆️👀 (Lineage prevalent in #Portugal)

* includes recently designated BA.2.x.y and undesignated BA.2s Image
BA.5*/BA.4* hotspots - #UnitedStates #15DayTrends

All eyes on #NewYork! ImageImage
Read 12 tweets
CDC #NOWCAST Variant Proportions Predictions
- #USA (6/25/22)

42% BA.2.12.1 (S:L452Q)⬇️
36.6% BA.5 (S:L452R/F486V) ⬆️ 👀
15.7% BA.4 (S:L452R/F486V)⬆️
5.7% BA.2⬇️

Get #Boosted and #MaskUp

Source: covid.cdc.gov/covid-data-tra

@CDCgov ImageImage
Variant Proportions - a closer look at the top circulating lineages in USA and HHS regions 1-10

BA.2.12.1 has peaked in all the HHS regions reporting

BA.2 has been outcompeted

BA.5 is surging in all HHS regions Image
Read 4 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

46.66% BA.2.12.1**,
23.33% BA.5^^,
12.15% BA.4^^,
7.64% BA.2,
4.24% BA.5.1^^,
1.29% BA.2.9 and
1.17% unassigned

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 6/27/22
#OmicronVariantUpdates #UnitedStates 06/27/22

Top 5 lineages:
BA.2.12.1, ⬇️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.4 ⬆️ (Spike: L452R)
BA.2 ⬇️
BA.5.1 ⬆️👀 (Lineage prevalent in #Portugal)

* includes recently designated BA.2.x.y and undesignated BA.2s
#SARSCoV2 lineages in USA (#15DayTrends)

Circulating #BA5*/#BA4* sub-lineages:
BA.5, BA.4.1, BA.5.2.1, BA.5.1, BA.4, BA.5.2, BA.5.3.1, BE.1, BF.1, BA.5.3

Assignments via: #Nextclade #PANGO - clades.nextclade.org
Read 13 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

50.65% BA.2.12.1**,
19.90% BA.5^^,
10.46% BA.4^^,
9.83% BA.2,
3.30% BA.5.1^^,
1.21% BA.2.3 and
1.09% BA.2.9

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 06/26/22
#OmicronVariantUpdates #UnitedStates 06/26/22

Top 5 lineages:
BA.2.12.1, ⬆️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.4 ⬆️ (Spike: L452R)
BA.2 ⬇️
BA.5.1 ⬆️👀 (Lineage prevalent in #Portugal)

* includes recently designated BA.2.x.y and undesignated BA.2s
#SARSCoV2 lineages in USA (#15DayTrends)

Circulating #BA5*/#BA4* sublineages:
BA.5, BA.4.1, BA.5.2.1, BA.5.1, BA.4, BA.5.3.1, BA.5.2, BE.1, BA.5.3, BF.1
Read 14 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

47.60% BA.2.12.1**
22.33% BA.5^^
11.44% BA.2,
10.48% BA.4^^
3.61% BA.2.12,
1.08% BA.2.9 and
1.05% BA.2.3

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 06/25/22 Image
#OmicronVariantUpdates #UnitedStates 06/25/22

Top 5 lineages:
BA.2.12.1, ↔️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.2 ⬇️
BA.4 ⬆️ (Spike: L452R)
BA.2.12

* includes recently designated BA.2.x.y and undesignated BA.2s Image
Read 12 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

46.33% BA.2.12.1**,
17.07% BA.5^^,
15.30% BA.2,
9.02% BA.4^^,
5.80% BA.2.12,
1.75% BA.2.3 and
1.21% BA.2.9

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 06/23/22 Image
#OmicronVariantUpdates #UnitedStates 06/23/22

Top 5 lineages:
BA.2.12.1, ⬇️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.2 ⬇️
BA.4 ⬆️ (Spike: L452R)
BA.2.12

* includes recently designated BA.2.x.y and undesignated BA.2s Image
Read 12 tweets
This is insane:
Only 54 percent of district health board staff have had the flu vaccine! Nelson Marlborough District Health Board: just 39 percent of workers had been vaccinated against flu.
If you can prevent infection with something (the flu) that harms kids, older people, pregnant women, and others...and kills some people every year, how can you be a health care worker and not bother getting vaccinated..to keep your patients safer?

Of course it should be required
Also this is becoming a trend, increasing/promoting free vaccines *after* a surge/peak
Prevention doesn't work that way.

We knew months ago that this would be a bad flu season, Australia got clobbered.
And yet we changed nothing.
Read 11 tweets
Free flu vaccine for:

• Pregnant women (any trimester)

• People aged 65 years and older

• Māori and Pacific peoples aged 55 to 64 years

• People aged under 65 years with certain medical conditions
• Children aged 4 years or under who have been hospitalised for respiratory illness or have a history of significant respiratory illness

...
Australia is getting hit rather hard by flu, now's the time for NZ to prepare.

The last thing anyone needs is flu and a repeat case of Covid.

If you've not been #boosted against #Covid, remember that repeated infections are
*to be expected* with Covid.
Read 4 tweets
Here are 2 family members, similar ages/#MedTwitter history, #vaxxed & #boosted, dev symptoms & tested pos same day, got Paxlovid same day. Day 4 tests below. Why are we still using a 'one size fits all' strategy to exit isolation when rapid tests are readily available, @CDCgov ?
I doubt policy will change (note: shortening isolation to 5d was done to minimize societal impact from loss of essential workers to isolation in Jan #Omicron wave), so you should choose to rapid test to exit isolation. A positive = contagious, no matter how many days it's been.
Here's another example. Two more people, again similar age/health history, both vaxxed and boosted. On the left, patient #1 on day #13. On the right, patient #2 on day #5. We'll see what happens with patient #2 but I'd be willing to bet they can leave isolation well before 2 wks.
Read 4 tweets
BA.2.12.1 is the top circulating lineage in the #UnitedStates

It has significant growth advantage over other circulating lineages in #USA

Cov-spectrum predicts a 47% growth advantage over BA.2* (over last three months)

Get #Boosted and #MaskUp!
Tracking Spike #L452Q mutation over time

Current Hotspot: #USA
Emerging Hotspot: #Canada

Tracker: public.tableau.com/app/profile/ra…
Tracking the rise of Spike L452Q mutation in #Canada

Hotspots: #BritishColumbia, #Alberta

Note: Many BA.2.12 (534 sequences) with Spike L452Q & Spike S704L (should have been designated as BA.2.12.1)
Read 8 tweets
There's another 🌊 of #COVID19, y'all. I have gotten more texts since Mon asking questions about monoclonal antibodies, about Paxlovid, about rapid tests, & on & on than I have in the whole month preceding. Be aware. All these folks tested at home & are uncounted in tallies.
This is anecdotal, but a pattern recently: people staying pos longer on rapid test. Here's an older pt, 4 doses Moderna #COVID19 #vaccine, mono Ab on d1, feels 100% now, & still quickly/strongly pos (ie very contagious) on d10. Had he not retested, he might be infecting others.
@CDCgov shortened isolation to 5d in Jan b/c they were concerned society may fail to function w/ huge #s of essential workers out for 10d in #Omicron surge. This has to be changed. People are leaving at d5 w/o masking or testing. They need to rapid test to exit or isolate longer.
Read 4 tweets
Well, it was fun while it lasted. And remember that official case counts are just the tip of the iceberg. Most people are being diagnosed via rapid testing at home & never appear in these totals at all. If you aren’t #Boosted, now’s the time. #MaskUp #COVID19
Let me add that my major reason for concern at this point is less about deaths in the short-term. Though we continue to lose a couple thousand Americans per wk to #COVID19, & it wasn’t mild for any of them, deaths are much lower than they’ve been in a long time. /2
I’m worried about the people we are now seeing with persistent cognitive impairment (like early dementia kind of symptoms), given that we now know #COVID19 can shrink the brain even in otherwise “mild” cases. forbes.com/sites/williamh…
Read 9 tweets
First sequence of BA.2.12.1, the #BA2 #Subvariant with #Spike #L452Q mutation is uploaded in @gisaid from #Arkasnas

This #Omicron #Sublineage has significant growth advantage over BA.2 and BA.1.1

Please get #Boosted!

Get #tested if you have any #COVID19 symptoms
Read 6 tweets
New #PANGO designations - BA.2.*

BA.2.4Alias of B.1.1.529.2.4, #Singapore lineage

BA.2.5Alias of B.1.1.529.2.5, lineage in #Portugal and other countries

BA.2.6Alias of B.1.1.529.2.6, lineage in #France and other countries

BA.2.7Alias of B.1.1.529.2.7, #USA lineage ImageImage
These are new designations - branching from the BA.2 subvariant

more to follow ..... will update key mutational differences and transmission advantage (if any)
BA.2.4 (aka B.1.1.529.2.4) | prevalent in Singapore

Key mutation: ORF6:M58K

COV-spectrum predicts a growth advantage of 14% over BA.2 and 46% over BA.1.1 in #Singapore

BA.2 and BA.1.1 are currently the dominant lineages in circulation in Singapore Image
Read 29 tweets
🧵As a scientist & physician, when our #pandemic predictions are off, I think it's important to circle back & analyze why. In late Dec 2021, I tweeted a🧵predicting widespread disruption of everything from health care & pharmacies to grocery stores & schools in Jan/Feb '22. 1/x
The reason for my prediction was the pattern of a huge spike in #COVID19 cases the prior winter (driven in part by holiday travel) & the fact that #omicron was considerably more contagious than prior #COVIDvariants & more able to evade immunity from vaccines or prior infxn. 2/x
The pace in growth of cases in Dec '21 in countries w/ early #Omicron outbreaks was stunning. The graphs were vertical. In the US, we appeared on target to have >500K cases/d in the US. We had no idea yet how long the surge would last. 3/x
Read 18 tweets
New data out today from #Denmark demonstrating that #Omicron #BA2 is more transmissible than #BA1 and has immune evasive properties reducing protective effect of #vaccination

Full 🧵👇
1/ medrxiv.org/content/10.110…
- Of 8,541 primary household cases with #Omicron, 2,122 were #BA2
- There were 5,702 secondary infections among 17,945 potential secondary cases
- In households with #Omicron, secondary attack rate was
29% - #BA1
39% - #BA2
2/ Image
- compared to #BA1, #BA2 associated with ⬆️ susceptibility of infection in
#unvaccinated (OR 2.19)
fully #vaccinated (OR 2.45)
#boosted (OR 2.99)
- ⬆️ transmissibility from #unvaccinated cases in #BA2 houses compared to #BA1 (OR 2.62) (Not seen in vaxd or boosted)
3/ Image
Read 4 tweets
1/🧵 WHY are Booster Rates so low⁉️

Only 1 in 4 Americans is Boosted. People get vaxxed & then bag the best protective approach.

I honestly don’t get it??

Let’s review some studies:

750k people boosted (Pfizer) showed 90% ⬇️ in death vs non-boosted.

bit.ly/33WQ2tK
2/ Another study of ~750k people showed vaccine (Pfizer) effectiveness at 7 days after 3rd dose w 93% effectiveness. WOW

BLUE (3 doses) on this graph shows WAY better protection than RED (2 doses) =
⬇️ hospitalization
⬇️ severe dz
⬇️ death

It’s clear!

bit.ly/3KuHDic
3/ And that explains clear results posted by @DrEricDing 👇 that show impressive reductions in hospital admissions…

You want to stay safe at home right??

You don’t want me as your doctor because that comes w an ICU & ventilator. Get #boosted.

Read on…
Read 6 tweets
📍Deaths are paralleling #COVID19 hospital admissions in Illinois—exponentially. (right is log axis)

📍Deaths in IL have also essentially tied last year’s all-time high.

➡️Now will they stop with “mild” finally? Let’s get #boosted & #N95/KN95 & #ventilated.

HT @DrWilliamKu
2) Other concerning news is that pediatric hospitalizations for #COVID19 in Illinois is growing fast as well as ICUs.
3) someone who eyeballed the numbers asked if 10% of those hospitalized die… It could be higher since those who die were probably hospital admitted a week prior or more. Though we can’t eyeball it exactly, it’s not single digit small it seems.
Read 3 tweets
1/

New research shows that only 10% #Omicron cases are in ppl who have gotten #COVID19 #Booster.

This may be MISINTERPRETED as:

"Only 10% of people w/ #BoosterDose get #OmicronVariant"

OR

#BoosterShots are 90% effective"

Not that simple! READ ON!

medrxiv.org/content/10.110…
2/

First, this is NOT a critique of the study (currently a pre-print).

Researchers at @MethodistHosp who did this provided a VERY valuable piece of info and are not making any inappropriate claims. Great work!

It's just that it's easy for public/media to misinterpret results!
3/

Paper reports on a total of 1313 #OmicronVariant cases in the Houston, TX area.

See table below:
~49% of cases in those not vaccinated (0 or 1 does)
~51% are #BREAKTHROUGHS.

Of those #Breakthrough cases,

535 cases w/ 2 #vaccine doses
140 cases w/ 3 doses (i.e., booster) Image
Read 18 tweets
This is horrifying. I expected this to happen at some point in Jan or Feb with #Omicron. I didn't expect it happen on January 1. 💔

🙏 to all of of the volunteer #firefighters & #EMS. Friends, please go donate to your local depts to honor their service. #MedTwitter #Maryland
Listen, important. Most adults in #Maryland are #vaccinated. Fewer kids are. MANY haven't yet gotten a #boostershot (only 70M in entire US pop of 331M #boosted). A booster will ⬇️ risk of hospitalization by 88% & starts protecting you in 7d with major protection in 14d. GO DO IT!
If you're #boosted, THANK YOU. Your job is to call 3 people age 16+ NOW who are #vaccinated but not yet #boosted & tell them to #GetBoosted ASAP. This is time-critical, esp w/ #schools to reopen in 36 hrs. #Baltimore #Maryland, appts here as soon as 1/4: umms.org/coronavirus/co…
Read 4 tweets

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