Discover and read the best of Twitter Threads about #breastradpath

Most recents (8)

1/ #BreastRadPath with @DrJordanaP

For this tweetorial we are going to talk about how we evaluate the biomarkers ER, PR, and HER2.

@BIDMCpath @BIDMC_BreastImg @CollinsLauraC @ADamronMD @GuzmanArocho @XeniaParisi @MarcosLepeMD @DrGeeONE @smlungpathguy
2/ The biomarkers provide predictive information (how a patient may respond to targeted therapy) as well as prognostic information. It helps to organize patients into treatment groups that follow different algorithms and guidelines.
3/ Biomarkers are evaluated in routine clinical mgmt of patients with breast cancer. The 3 routinely tested:

Hormone receptors (HR): Estrogen receptor (ER) and Progesterone receptor (PR)
Human epidermal growth factor receptor 2 (HER2)

(chart from:
Read 18 tweets
The craziness of the past week has settled down and #Breastradpath with @LizaMQuintana is back with Case 4!

53 yo had a screening MG. Maybe some new calcs or distortion in rt breast (arrow, 3D not shown)? #radres #radfellows -which images would you want during diag work-up?? Image
She returned for diag work-up. Common diag w/u is mag views for calcs and tomo spots/90 for poss AD. But we decided to start with #contrastmammo & use enhancement to triage. What do you think? Based on these images alone, does it change your level of concern???? Ddx??
Rather than showing you other diag images, which weren't that helpful, I'm showing the US. Could this be a correlate??? Does it change your level of concern?? Ddx??
Share thoughts below.... more to come tomorrow! Image
Read 13 tweets
1/For this tweetorial in our #breastradpath series w @LizaMQuintana we're going to focus on #malebreastcancer for male breast cancer awareness week. An important topic that doesn't get enough attention! #BCAM @MBCC_MHBT @BreastCancerMen @BreastCancerNow @BreastImaging @Breast360
2/But before we can talk about the male breast, we first need to review the female breast. The female breast is made of skin, breast fat, ducts, and lobules. The breast sits on the pectoralis major muscle of the chest wall
3/The female breast is like a tree in springtime. A group of buds on a tree are like breast lobules (one bud is called an acinus). The tree branches are like breast ducts. Can you see the similarities between the sakura cherry tree and the specimen of breast tissue below???
Read 18 tweets
#breastradpath with @DrJordanaP

For #BreastCancerAwarenessMonth month we want to review the process from imaging to diagnosis of breast cancer. 1/ Image
It starts when a patient comes in for a screening or diagnostic mammogram. Here is @DrJordanaP reviewing #mammograms in the reading room. 2/ Image
Please review screening modalities in this amazing tweetorial from last week from @DrJordanaP! 3/

Read 24 tweets
1/ Let the tweetorials begin for our #breastradpath series with @LizaMQuintana! We're starting with the basics of screening mammography for #BCAM

Each screening mammo has 4 images-2 of the right breast and 2 of the left. If any abnormality is seen then we get more images
2/ There are 2 main areas on all mammograms - white areas are glandular tissue (part of breast that makes milk, yellow on image) & black areas are breast fat (blue). All women have both but in different proportions #breastdensity
3/ Check out what this looks like on the pathology slide. And just to give some definitions: adipose tissue=breast fat, terminal duct lobular unit=glandular tissue, stroma=supporting structure of breast #Breastpath
Read 18 tweets
Case 3 #breastradpath with @DrJordanaP

44 yo woman. On req: "faint grouped microcalcs." #breastimagers separate calcs and no calcs cores into separate containers (so helpful!). There was only one block of cores with calcs. Here are the #breastpath images. Thoughts? Next steps? ImageImage
You are all thinking the way I did! For cases with calcs, I always review the imaging, and in particular the specimen radiograph, to see the morphology of the calcs I should look for. Check out the imaging from @DrJordanaP 👇

The tiny calc in the initial levels of the CNB are not the same as the calcs seen on imaging. We need to find those calcs --> LEVELS! (I haven't heard it called steps before! I like!) #breastradpath correlation is so important here! ImageImage
Read 11 tweets
Case2 of #breastradpath with @LizaMQuintana

40 yo with focal asymmetry in rt breast on screening mg (blue arrows). See descriptions below all images.

#radres #radfellows #breastimaging #breastpath #pathology #breastmulti @BIDMC_BreastImg @BIDMCpath @DrTedJames Screening mammogram from to...
Patient returned for diagnostic #contrastmammo which confirmed focal asymmetry (blue arrows) & showed non-mass enhancement (NME) on recombined images (yellow arrows). US showed correlate. USG core done and post-MG confirmed target (yellow arrows). Contrast enhanced mammogram...Targeted ultrasound of the ...US guided core biopsy was d...
Calling all breast docs, what is your differential diagnosis? BI-RADS? Next steps??
Read 9 tweets
#breastradpath with @DrJordanaP

We are excited to share the first case in our #breastimaging and #breastpath correlation series! This case highlights challenges of imaging/management and the pathologic diagnosis.

@BIDMC_BreastImg @BIDMCpath #radres #radfellows Image
56 yo woman with left breast focal asymmetry and calcifications. Screening mammogram. @DrJordanaP Image
Diagnostic mammogram and ultrasound were performed. A presumed ultrasound correlate was found with calcs and vascularity. What is the next step? What BI-RADS would give? @DrJordanaP ImageImage
Read 17 tweets

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