Discover and read the best of Twitter Threads about #bsh2017
Most recents (14)
Prof Dave Roberts now taking us through whether we should genotype all blood donors #BSH2019
Alloimmunisation is a significant source of morbidity and also causes a lot of extra work and time delays for treatment. Therefore best avoided if possible #BSH2019
12-15% sickle patients in a large centre who could benefit from exchange transfusion are not having this procedure as blood is not available for them due to having developed multiple antibodies #BSH2019
Medal lecture: Judith Marsh on How I treat aplastic anaemia #BSH2017
When assessing new pts don't discount 'asthma' or 'alcoholic liver dx' which may be pulm fibrosis or cirrhosis due to BMF syndrome #BSH2017
Disease severity is clearly outlined in the @BritSocHaem guidelines onlinelibrary.wiley.com/doi/10.1111/j.… #BSH2017
Katherine Colman, medical student from Australia presents her work w Sue Pavord in Oxford last year on IDA in pregnancy #BSH2017
Good précis of pros and cons of oral and iv iron. Extravasation of IV iron often forgotten cause of morbidity #BSH2017
In Katherine's study refractory to oral iron allocated to oral fe+counselling or IV iron by physician judgement #BSH2017
Catch up from the BBTS session to follow... now its thrombosis free comms and Laura Green presenting ORANGE #BSH2017
Annual major bleeding rate for pts on oral anticoagulants 1.2-3.6% in trials, almost certainly higher in real life #BSH2017
Warfarin is one of the drugs most frequently wrongly prescribed and dispensed #BSH2017
David Rees on stroke prevention in children w sickle cell. At KCH they screen S/bthal & SC although not included in original data #BSH2017
20-30% inadequate scans in 2-3 yr olds -poor cooperation but stroke risk highest in this age. MR under GA if still no scan by age 3 #BSH2017
What to do with persistently abnormal TCD despite tx ?add HU ??consider HSCT? #BSH2017
Austin Kulasekararaj on extending remission beyond transplant in MDS #BSH2017
<5% pts with MDS undergo transplantation
Of those transplanted, 35-40% are cured #BSH2017
Of those transplanted, 35-40% are cured #BSH2017
Clone will not be eradicated prior to transplant as HMAs do not affect stem cells but presence of clone post BMT predicts relapse #BSH2017
MDS session is next. Dr Ana Carvalhosa with a case presentation #BSH2017
Additive effects of driver mutations in MDS on leukaemogenesis: more mutns = increased risk of leukaemia #BSH2017
Relatively new terms emerging in MDS: ICUS, CHOP, CCUS #BSH2017
Next the 2 highest scoring abstracts. PNH and aplastic anaemia - Anita Hill and Morag Griffin #BSH2017
Immune hit on marrow in AA tends to spare PIG-A mutated PNH clone, hence allowing expansion #BSH2017
What is the impact of concomitant use of ATG and eculizumab? Increase in infection doesn't appear to be a problem #BSH2017
Day 2 of #BSH2017 and am going malignant for a change.... MPDs coming up
Dr Jyoti Nangalia on genetic influences on phenotype in MPD #BSH2017
How can 3 genes cause 1 phenotype and how can 1 gene cause 3 phenotypes? #BSH2017
Dr Danielle Freedman talking on Lab Tests Online @LabTestsUK #BSH2017
Pt involvement in care is key - but also that they understand their test results #BSH2017
Active involvemt of pts &access to own results does not appear to increase anxiety for pts or work for drs -opposite demonstrated #BSH2017
Suthesh Sivapalaratnam on unexplained bleeding problems and thrombogenomics #BSH2017
One stop DNA assessment for pts w bleeding phenotype and no known diagnosis... free for 2017 #BSH2017 thrombogenomics.org.uk
Careful interpretatn always needed when mutations found not already described in multiple families causing bleeding phenotype #BSH2017
Lab science and John Burthem talks on digital morphology &the UK NEQAS scheme #BSH2017
Talking through thought processes involved in making morphological diagnosis - simplification &prioritisatn happens subconsciously #BSH2017
Digital morphology has many advantages but a few drawbacks inc permanent record (including which bits of film were looked at!)... #BSH2017
Next Dr Caroline Millar on von Willebrand disease - starting with does the pt require treatment? #BSH2017
When does low vwF become type1 vWD? polymorphisms& mutatns in vWF gene, ABO gp &other genetic &non genetic factors all pay a role #BSH2017
Levels may be low but ?do they contribute to bleeding risk &/or explain bleeding phenotype? #BSH2017
Now in the bleeding session and Peter Collins is talking on role of fibrinogen in bleeding #BSH2017
Making distinction between lab test results and ability to stop bleeding in vivo #BSH2017
Does higher fg = better ability to control haemorrhage? Or does it just make clot stronger? Once above 2g/L does the value matter? #BSH2017
