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How could you use IV to analyze #CABANA? I haven't seen the publication (is it published?) and am going mostly on what people have tweeted. But if most of the crossover happened early, before patients experienced endpoints, then it could be pretty straightforward...
Getting randomized to ablation in the trial meant that you were very likely to get it, but not in all cases. Similarly, getting med Rx meant very likely to get med Rx, but not in all cases. So the breakdown is something like below.
If you imagine that the populations in both arms are identical (which is true on average), then for every patient in one arm, there is his/her equivalent doppleganger who is identical in all ways, except got randomized to the other arm.
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