Discover and read the best of Twitter Threads about #cancergroundshot

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This is going to be a thread of our #MCBS session starting in a couple of minutes at #ESMO22. Follow along for a LIVE tweet-summary of our session! @myESMO @ChernyNathan @VriesElisabeth 1/
First, @ChernyNathan is giving an overview of cancer drugs approved by FDA in last 5 years. For more, read his excellent paper in @NatRevClinOncol published earlier this year. @DianaNrco
IO drugs made up almost half of these drug approvals. #ESMO22
Read 27 tweets
Hi, #ASCO21 world. As you get bombarded with news of the remarkable new therapies, I request you to kindly read these 3 papers to put things into context.
1. Trials that are flawed in design, analysis, and interpretation can give false signal of benefit- esmoopen.com/article/S2059-… 1
2. Drugs that are claimed to be "well-tolerated" or having a "favourable" or "Acceptable" toxicity profiles are usually not so. These are almost misnomers. Look into the safety data yourself. bmj.com/content/363/bm… 2
Patients in LMICs are still dying not because they didn't have access to the newest checkpoint inhibitor but because they didn't have access to surgery/radiation/pathology/chemo and other basic services. #cancergroundshot #globaloncology thelancet.com/journals/lanon…
Read 3 tweets
Published just now in @ASCO_pubs JCO Global Oncology. The FIRST report of a population-based cancer registry from Nepal. It felt very meaningful to contribute to this #cancergroundshot project. ascopubs.org/doi/full/10.12… #globaloncology Image
For the first time, we now have official data on the commonest cancers in Kathmandu by incidence and mortality in different subgroups of population. ascopubs.org/doi/full/10.12… Image
The population-based cancer registry has only just started in Nepal, and there are plenty of room for improvement. But I hope this provides the foundation for stronger work in the future. ascopubs.org/doi/full/10.12… Image
Read 4 tweets

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