Discover and read the best of Twitter Threads about #ccm

Most recents (11)

Feb 27th 2023
#MIGRATION Aujourd’hui, 400 scientifiques signent une tribune historique sur @lemondefr pour demander la tenue d’une convention citoyenne sur la migration. D’où vient cette idée, pourquoi peut-elle tout changer et comment aider ?

#Thread ⤵ 1/N
Fin 2022, le gouvernement annonçait son nouveau projet de loi “Asile et Immigration” présenté le 1/02/23 en Conseil des ministres bit.ly/41wwWnC
Indépendamment du “fond”, dénoncé par de nombreuses associations et journalistes, cette loi pose 2 problèmes majeurs :
2/N
1⃣ il s’agit de la 22e loi sur le sujet en 30 ans !
Comme l’explique @ARTEInfo “Notre étude révèle une complexification et un durcissement progressifs du droit des étrangers avec, en arrière-plan, la montée de l’extrême droite en France” arte.tv/sites/story/re…
3/N
Read 15 tweets
Oct 15th 2022
Last April I defended my #PhD at @KU_Leuven, in which I developed ways of looking at the #Force within your cells...

(1/20) 🧵In this #ThesisThread I will tell you exactly how I did it...
(2/20) No, at least in our galaxy, our cells do not have #midichlorians. But all ~30 trillion cells of your body are able to:

🔍Change their behavior if they #feel changes in the forces around them...

💪Exert #forces to move or to explore the environment
(3/20) Let me give you an example:

🚀When astronauts spend time in space, their bones become weaker! This means that the cells of their bones take a decision when they don't feel the #gravity anymore!

If there is no need, why should cells bother and maintain bones? Image taken from: https://w...
Read 21 tweets
Oct 4th 2021
#WeekendLecture
#GeneticsAndStroke

#Genetics is involved in several #stroke related conditions, such as small vessel disease #SVD, aneurysms, dissections, cavernomas, and intracranial #hemorrhages

Check this 🧵!
Prepared by @J_Rosales_MD
Edited by @interneurona Image
#Weekendlecture

#Genetic & #SVD
🧬🧠

✅1,5% of cerebral #SVD are #monogenic disorders
✅AR, AD or X-linked
☝🏼Absence of family history doesn't rule out diagnosis because of
👉de novo mutation
👉reduced expression or
👉incomplete penetrance
ahajournals.org/doi/10.1161/ST…
#Weekendlecture

#Genetic & #SVD

When to #suspect?🕵️‍♀️

✅early onset stroke without vascular RFs
✅systemic features and neuroimaging of an specific monogenic disorder
✅consanguinity
✅negative work up for other causes of SVD

👉ahajournals.org/doi/10.1161/ST… Image
Read 15 tweets
Jun 5th 2021
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses. Image
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011 Image
The influence of #HLA genotype on the severity of #COVID19 infection
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic. Image
Read 199 tweets
May 18th 2021
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action. jjcouey.medium.com/5-concerns-abo…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus. Image
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component. Image
Read 213 tweets
Mar 1st 2021
Reducing #COVID19 #Airborne #Transmission Risks on #PublicTransportation Buses
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%. Image
🔝#SARSCoV2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies. Image
High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others Image
Read 236 tweets
Feb 16th 2021
⚠️#Ocular #MRI Findings in Patients with Severe #COVID19: A Retrospective Multicenter Observational Study
» doi.org/10.1148/radiol…
All patients had nodules in the macular region, 8/9 (89%) had bilateral nodules, 2/9 (22%) had nodules outside the macular region. Screening needed. Image
⚠️🔝New-Onset #IgG #Autoantibodies in Hospitalized Patients with #COVID19
» doi.org/10.1101/2021.0…
An international team of researchers studying COVID-19 has made a startling and pivotal discovery: The virus appears to cause the body to make weapons to attack its own tissues. Image
⚠️🔝Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance
» academic.oup.com/eurheartj/adva…
Damage to the heart found in more than half of #COVID19 patients discharged from hospital who show raised levels of troponin. Image
Read 235 tweets
Oct 27th 2020
1/ #ZanzibariLivesMatter:As someone who has closely followed/wrote about the #Zanzibar Question in #Tanzania for 10+ years,I would say the seeds of what is happening now were watered in 2015 after a failure of fully implementing the Zanzibar Accord that worked a bit okay in 2010.
2/ #ZanzibariLivesMatter:At the heart of the #Zanzibar Accord was the realization that ‘Winners Take it All’ is not feasible for such a polarized #polity-it thus enshrined in the #Constitution some sort of a power sharing agreement that somewhat worked in 2010 but failed in 2015.
3/ #ZanzibariLivesMatter:From 2015 virtually all keen #observers of-and key #players in-#Zanzibar knew that 2020 is a ticking bomb,but differed in how to diffuse or preempt it;the ruling party,#CCM,opted to do so by clipping the wings of the then main opposition party there-#CUF.
Read 8 tweets
Aug 25th 2020
We' ll continue our vasoactive medication review with our old frined dobutamine! #chestcritcare
It is primarily a Beta-1 agonist, but it acts on Beta2 and alpha as well, making it a great inotrope, and also an ok vasodilator (in high doses alha agonism kicks in, and some vasoconstriction may occur

cfrjournal.com/articles/Inotr…
Dobutamine is used in the treatment of cardiogenic shock, it improves symptoms, but it has been associated with increased in-hospital mortality and future HF readmissions. It is also associated with arrhythmias and it has been rarely associated with eosinophilic myocarditis.
Read 7 tweets
Jun 9th 2020
I know ccm #worship is not everyone’s thing, but I’ve been mulling over the worship music industry lately as it relates to racial justice... It’s so complicit in holding up white supremacy but ppl all around the world sing these songs everyday.1/
What responsibilities to #worship leaders have when it comes to choosing these songs for worship? 2/
I think the time is over where #worship leaders say, “I’m just here to sing my songs to the Lord. I don’t have involvement in racism.” 3/
Read 9 tweets
Mar 20th 2020
🚨 New Guideline Published 🚨

Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with COVID19 🦠

Tweetorial on key clinical recommendations 👇🏻#CCM #ICM #COVID19 @ESICM @SCCM @CritCareMed
1️⃣COVID19 Testing in the ICU 🔬

➡️If pt is intubated, lower respiratory tract samples preferred > upper respiratory tract 🧫

➡️➡️Lower respiratory samples, prefer endotracheal aspirate >> bronchial wash or bronchoalveolar lavage 🧪
2️⃣Infection Control in the ICU

✅Recommend video-guided laryngoscopy for intubation

✅Aerosol-generating procedure➡️ require a negative pressure room & HCPs should wear fitted respirator masks + PPE

✅Non-ventilated OR non-aerosol-generating procedure➡️ med/surg masks + PPE
Read 8 tweets

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