Discover and read the best of Twitter Threads about #cdifficile

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@MondayNightIBD @Spencerkelley7 1/

👋 to this week’s #MondayNightIBD with the #Back2Basics #B2B team

🦠 Today we are discussing #Cdifficile infection in #IBD

Stay tuned to 📝 more about #CDI :
➡️ #IBD vs. general 👩👨‍🦱
➡️ diagnosis
➡️ treatment options Image
@MondayNightIBD @Spencerkelley7 @dunleavy_katie @SanjeevaniTomar @yaransarkis @RomyChamoun @BassiMehak @JosephHabibi_MD @DCharabaty @DSTEINGIMD @BeniwalPatelMD 2/

#CDI in #IBD compared to general 👩👨‍🦱

⬆️⬆️ common (5-8x 🔺)
⬆️ community-acquired
⬆️ w/o antibiotic 💊 exposure
⬆️ colonization
⬆️⬆️ recurrence ☹️
⬆️ colectomy risk 🔪

🚨 often no pseudomembranes on 🔦
🚨 can happen post-colectomy 🔪 in #smallbowel or #IPAA
@MondayNightIBD @Spencerkelley7 @dunleavy_katie @SanjeevaniTomar @yaransarkis @RomyChamoun @BassiMehak @JosephHabibi_MD @DCharabaty @DSTEINGIMD @BeniwalPatelMD 3/

Testing for #CDI ⬇️

💩 GDH:
✅ detects organism
⬆️ sensitive
⬇️ specific

💩 PCR:
✅ detects genes that code for toxin
🚫 detect toxin
⬆️ sensitive
⬆️ specific
🚨 can over-diagnose

💩 EIA for toxin A/B:
✅ detects toxin
⬆️ specific
⬇️ sensitive
🚨 can under-diagnose
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