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After a year since #biorxiv, I am glad that this story found its home at @Dev_journal. Huge thanks to my colleagues @GurdonInstitute @MarioniLab, and people who reached out after #biorxiv submission! Here is the lengthy Tweetorial and some notes.
journals.biologists.com/dev/article/do…
We want to know why mammals fail at regen their arms or legs. However, we do not even know if we have cell types to perform such a feat.
To answer this, we use pre-metamorphic frogs/tadpoles. Gladly, my leg doesn’t look like a frog leg, but tadpoles are the most similar lab animal developing their limbs like mammals and can regen limbs + older they get, they fail at regen. So, what`s going different?
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