Discover and read the best of Twitter Threads about #chromatography

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How are mRNA vaccines made? A chemist’s perspective. TL;DR A DNA plasmid is used as template for the in vitro transcription of DNA to mRNA which is then packaged in a lipid nanoparticle. But it is a bit complicated than that. (image @AFox_Perth theconversation.com/australia-may-… ) 1/35
I am chemist with a life-long interest in viruses and self-assembly, working in the nanomedicine @ARCCoEBionano field for over 10 years. More recently, our group has been synthesising short RNA (unpublished work) with my colleague #ozchem @Fahrenbachus @UNSWScience 2/35
So when I heard first about mRNA vaccines back in April I was fascinated. Since then I have also become part of group mentioned in theconversation.com/australia-may-… article by @AFox_Perth that is arguing the case for local mRNA (and other RNA + DNA products) capabilities in Australia 3/35
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