Discover and read the best of Twitter Threads about #cim

Most recents (3)

Not mutually exclusive, but most people said they'd prefer seeing rather than joining a discussion to analyze THAT erythritol paper, and I have some airport hours ahead...

Here go🧵.

In case you've been living under a rock, this is the paper:

nature.com/articles/s4159… Image
Relevant disclosures for interpreting my interpretation?

I'll speak more as a clinician clinician who sees many ⬆️CVDrisk patients following a low-carb diet than as a healthy adult who follows a low-carb diet and occasionally consumes erythritol.
Things I liked about the paper = ✅️.

Things I didn't like (and matter) = ⚠️

Things I didn't like (and are nitpicking) = 🧐.

🩸[] = blood concentration.

CVD = CardioVascular Disease.

MACE = Major Adverse Cardiovascular Events.

Why we "liked" erythritol in the first place?
Read 32 tweets
1/18) 🚨NEW PAPER in @AJCN provides evidence supporting #CIM of #obesity

👉 Glycemic Load >>> Calorie Counting for weight loss

👉 Biomarkers of Low carb diet predict weight

👉Insulin hyper-secreters especially benefit fromlow-carb

Video 👉👉
🧵... Image
2/18) First, and foremost, a big congrats to @AdrianSotoMota and @davidludwigmd for an excellent work!

& of course, for those who have the time, I highly recommend reading the full paper, here: doi.org/10.1016/j.ajcn…

But for those who prefer video or TW thread... HERE WE GO...
3/18) What the researchers did in this paper is perform a secondary analysis of pre-existing data from a 12-month RCT: the DIETFITS trial in which 609 adults aged 18-50 without diabetes were randomized to either a 12 m Low-carb diet (LCD) or low-fa diet (LFD).
Read 18 tweets
⚠️NEW PAPER⚠️
@AJCNutrition with: Mark Pereria, Cara Ebbeling, @LuciaAronica & @davidludwigmd

doi.org/10.1016/j.ajcn…

With many of my favorite things:
1) Open Science.
2)Critical analysis of high quality research.
3) Causal inference.
4) #CiCo vs #CIM
5) 1600 lines of R code.
This is a post-hoc analysis of the DIETFITS, a high-quality RCT from @StanfordMed lead by @GardnerPhD (who kindly reviewed an earlier version of our manuscript) which compared carbohydrate vs fat restriction to achieve weight-loss during one year.

jamanetwork.com/journals/jama/…
This trial found non-significant weight-loss differences between both diets.

Additionally, no interaction was observed with genotype nor hyperinsulinemia.
Read 24 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!