Discover and read the best of Twitter Threads about #circadian

Most recents (7)

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Skeletal muscle does not only have a #circadian clock in ๐Ÿชฐ๐Ÿญ BUT also in ๐Ÿ‘จโ€๐Ÿฆฑ!

Ever wondered how muscle metabolism changes over 24h?

& how about young healthy vs. older metabolically-compromised men?

Then follow this ๐Ÿงต on our new work @CellReports
sciencedirect.com/science/articlโ€ฆ
@CellReports /2
To study skeletal muscle metabolism around the clock, we combined data from 2 of our previous human studies with 2 distinct cohorts:
young healthy vs. older metabolically-compromised men

In both cohorts, 5 m. biopsies were taken on a single day:
8AM, 1PM, 6PM, 11PM & 4AM Image
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Volunteers received 3 standardized meals & went for a standardized walk 1h after each meal. Before each biopsy, indirect calorimetry was performed to determine energy expenditure & respiratory exchange ratio. Also, blood was drawn bihourly & core temperature @BodyCap measured. Image
Read 21 tweets
July 2021 #mdpi
#covid19 Key Emphasis on #Melatonin Safety and Therapeutic Efficacy

"it likely that multi-tasking melatonin will provide multi-protection, maintaining its efficacy against the virus variants that are already emerging and will emerge"
mdpi.com/2076-3921/10/7โ€ฆ
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"Melatonin is a systemic dealer that".."brings into play its cooperative triad, antioxidant, anti-inflammatory, and immune-stimulant backbone, to stop the infective cycle of SARS-CoV-2 or any other endogenous or exogenous threat.
2/
"In COVID-19, the corporal propagation of
SARS-CoV-2 involves an exacerbated oxidative activity and therefore the overproduction of great amounts of reactive oxygen and nitrogen species (RONS)."
3/
Read 23 tweets
You've heard of #IntermittentFasting, but do you know the science? That's where @nutritionorg comes in! The next session features @DrKristaVarady, @LongoOnlus, @SatchinPanda, & @Kelsey_Lifts. #Nutrition2022 #NutritionLiveOnline
First alternate day fasting and time restricted eating (TER). #Nutrition2022 #NutritionLiveOnline
There are 3 types of intermittent fasting: alternate day (ADF), 5:2, and TRE. What do clinicians fear about ADF? Binging. #Nutrition2022 #NutritionLiveOnline
Read 46 tweets
Hot but not bothered?๐Ÿง ๐Ÿ”ฅ Our paper on human brain temperature is out today in Brain! @ONeill_Lab @MRC_LMB @Brain1878 #LMBResearch #BrainTemp #BrainTrauma doi.org/10.1093/brain/โ€ฆ
With thanks to our amazing participants, collaborators, and supporters @AriErcole @Etherjoe @ManuelCabeleira @CescaStats @EdinUniImaging @EdinUniNeuro @EdinUniBrainSci @CenterTBI @CellBiol_MRCLMB @RachelSEdgar and @The_MRC for funding
In a prospective analysis of healthy men and women, we found that brain temperature is higher than body temperature; brain temperature ranges from 36.1 to 40.9ยฐC, with an average of 38.5C ๐Ÿง ๐Ÿ”ฅ.
Read 11 tweets
#2 B-COMPLEX/MULTI VITAMIN. Buy a liposomal or other form that increases bio-availability. Take 1 capsule w/Breakfast and Lunch. If you have stomach upset, try sublingual (under tongue) EZ Melt B-Complex in AM & Multi w/iron for Dinner. amazon.com/Liposomal-Methโ€ฆ
#3 OMEGA 3s. Fish Oil, Krill Oil, Algae Oil are all good sources of Omega 3. Be careful the EPA/DHA ratio. EPA helps with inflammation/DHA helps with cognition. You need both! Opt for a 1:1 or 2:1 ratio of DHA to EPA (2:1 ratio eg. 800 DHA/400EPA) amazon.com/3Care-Concentrโ€ฆ
Read 93 tweets
My story starts in a small town from the northern region of the warm vibrant and culturally diverse #India.
#VoicesIWS Image
Born as 3rd daughter in a culture where birth of a daughter is resented by many, my parents had to deal with 'eerie' solutions from society to get rid of the "burden" that I was about to become. But, my visionary parent-warriors had their armours on! ๐Ÿ˜‡
#genderbias #VoicesIWS
Read 15 tweets
@AGA_Gastro highlights #NASH #NAFLD first up @VidalPuig Where do the fatty acids go? sciencedirect.com/science/articlโ€ฆ
#NAFLD #NASH How much does the clock matter for pathophysiology or therapeutics #circadian sciencedirect.com/science/articlโ€ฆ
โ€œLost in Translationโ€ or Utility at Last? NASH biomarkers #genetics and risk prediction beyond PNPLA3 sciencedirect.com/science/articlโ€ฆ
Read 6 tweets

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