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RE: general principles underlying #SARSCoV2 testing for #Covid_19:
1) true: the tests may be based on technology/techniques that are decades-old and “any grad student could do.” That doesn’t mean one can develop/scale-up a clinical-grade test quickly/easily 1/18
1) true: the tests may be based on technology/techniques that are decades-old and “any grad student could do.” That doesn’t mean one can develop/scale-up a clinical-grade test quickly/easily 1/18
The difference between a research and a clinical test is how the performance characteristics must be understood clinically. If you’re going to screen 1000s of patients, and use the results to clear negative patients, you have to understand how often you’ll get it wrong 2/18
In this case, we should be very concerned with the sensitivity of the test (false negative rate). If it’s even as low as 90% that’s potentially thousands of people who have the virus sent back into their communities. 3/18
