Discover and read the best of Twitter Threads about #cmd

9/19
#Tweetorial #CMD #ACC21

#CMD shares similar RFs w epicardial atherosclerosis (traditional ASCVD RFs) & is associated with several biomarkers of inflammation, oxidative stress & coagulation

🔗futuremedicine.com/doi/10.2217/fc…
🔗sciencedirect.com/science/articl…
🔗atherosclerosis-journal.com/article/S0021-…

10/19
#Tweetorial #CMD #ACC21

There is significant overlap between #CMD & epicardial disease

Large number of patients w/ #CMD also have epicardial atherosclerosis (obstructive or non-obstructive) & epicardial endothelial dysfunction

🔗onlinelibrary.wiley.com/doi/abs/10.100…

11/19
#Tweetorial #CMD #ACC21

In our IVUS study:
✅ Most patients with #CMD had significant plaque burden
✅ Patients with #CMD had higher plaque burden & more diffuse atherosclerosis as compared to patients w/o CMD

🔗jacc.org/doi/full/10.10…

Read 11 tweets

#CMD #Tweetorial

⚡ Coronary Microvascular Dysfunction ⚡

1/19

📌 What Is #CMD❓
📌 Why Is #CMD Important❓

Based on my #ACC21 #ACCImaging presentation

2/19
#Tweetorial #CMD #ACC21

Let’s start by talking about angina

✅ Angina w/o obstructive CAD is very prevalent

🔗ahajournals.org/doi/full/10.11…

3/19
#Tweetorial #CMD #ACC21

✅ Angina ➡ poor prognosis
✅ Angina with no obstructive CAD = ⬆ risks of CV events compared to no angina, even after adjusting for traditional RFs & co-morbidities

🔗academic.oup.com/eurheartj/arti…

Read 9 tweets

Join us at #ACC21 to learn about #CMD

✅ What Is #CMD & Why Is It Important?
✅ Dx & Risk Stratification of #CMD: Stress Testing & Noninvasive Imaging
✅ Catheter-Based Techniques in Dx of #CMD
✅ Emerging Link Between #CMD & #HFpEF
✅ Phenotype-Based Mngmt of #CMD

#ACC21 #CMD session details 👇

📅 Sat, May 15
⏰ 2PM

#ACC21 #ACCImaging #CMD session starting in 15 mins
Don’t miss this educational session

Read 8 tweets

https://twitter.com/coronarydoc/status/1309649449162092544

#Tweetorial on #ASNC2020 session

⚡Selecting Between Different Functional Tests⚡

☢ vs 🧲 vs ⏺ ❓

🔘 Strengths/Limits of Lesion Specific vs Myocardial Ischemia
🔘 Comparing Dx Accuracy of Tests
🔘 Ischemia Testing in #INOCA
🔘 How to Select Best Noninvasive Test

1/9

https://twitter.com/coronarydoc/status/1309649449162092544

#ASNC2020 #cvNuc
2/9
Dr Di Carli

☢ Issues with proposed #FFR threshold 0.8
☢ Exercise MPI correlates well with FFR but not at 0.8
☢ Benefit of FFR-guided revasc dominantly occurs w/ thresholds <0.8
☢ Quantification of lesion-specific #ischemia insufficient for patient mgmt

#ASNC2020 #cvNuc
3/9
Dr Di Carli

Lesion-specific #ischemia measurements (FFR/#FFRCT)

☢ Strength
Validated against ETT/MPI
Strong outcome data
Guidelines supported

☢ Limit
Controversial threshold (0.80 vs MPI-validated 0.66)
⬆ microvasc resist causes FFR pseudonormalization

Read 11 tweets

@mdicarli

☢ Selecting Between Different Functional Tests in 2020? ☢

This should be most interesting session of virtual #ASNC2020

I am excited to be virtual moderator w/ expert speakers Dan Berman, Keon Nieman, Paul Knaapen, @mdicarli, @VTaqMD

#cvImaging #cvNuc #CardioTwitter

@mdicarli

Are you ready for most exciting #ASNC2020 session?

⚡Selecting Between Different Functional Tests⚡

☢ vs 🧲 vs ⏺ ❓

Let’s hear from #cvImaging giants
Keon Nieman, Paul Knaapen, @mdicarli @VTaqMD @danielbermanmd

📆 Sat, Sept 26
⏰ 2:15 to 3:30PM
🗒 bit.ly/333dRNO

☢ This super exciting session starts in 3 hours ☢

📺 Tune in #cvNuc peeps to learn who benefits from ischemia testing & how to select best non-invasive test

⏰ 2:15 to 3:30PM
#ASNC2020

Read 9 tweets

Ben Hawkes

@benhawkes

https://twitter.com/USCERT_gov/status/1260259518862286849

This is a list of the most commonly exploited vulnerabilities between 2016 and 2019, from CISA and FBI. Unfortunately they didn't share their methodology, but let's take a closer look at the CVEs, because I think the list shows an interesting trend.

https://twitter.com/USCERT_gov/status/1260259518862286849

1) CVE-2017-11882 - A stack overflow in Equation Editor (EQNEDT32.EXE) that was accessible via Microsoft Office documents. Crucially, neither DEP or ASLR was enabled on this binary, meaning that the issue was trivially exploitable.

2) CVE-2017-0199 - Logic/design flaw in embedded HTA documents, exploited via Microsoft Office documents. This issue was originally exploited as a 0day by FINSPY and LATENTBOT.

Read 22 tweets

@iamritu @onco_cardiology @ErinMichos @khurramn1 @RonBlankstein @afshinfarzan @RBP0612 @NitiCardio @NadeenFaza @SinghVasvi @tiffchenMD @DocStrom @Michel_CorbanMD @DrMichaelShapir @RezaEmaminia @almallahmo @PanithayaC @DrMarthaGulati @ShelbyKuttyMD @MasriAhmadMD @DrRyanPDaly

Attending #ACC20/#WCCardio?
On behalf of #ACCImaging Section, I invite you to join us & learn from experts in an imaging-focused #CMD session

⭕ What is #CMD?
⭕ Role of non-invasive imaging
⭕ Role of catheter-based imaging
⭕ Link between #CMD & #HFpEF
⭕ Phenotype-based mgmt

https://twitter.com/ToddVillinesMD/status/1234147607326359556

Do not miss this #ACCImaging Highlight Session at #ACC20/#WCCardio 👇

We have a great program & expert speakers providing imaging highlights of meeting

https://twitter.com/ToddVillinesMD/status/1234147607326359556

@iamritu

@TomJFord

1/7
Very important descriptive study 👇 expanding our understanding of burden of #CMD + endothelial dysfunction in #INOCA (angina) by @TomJFord @ColinBerryMD
@CircIntv

⚡️ Let’s have a short #Tweetorial ⚡️

https://twitter.com/CoronaryDoc/status/1206041505430999042

2/7
Pre-specified analysis of CorMicA
onlinejacc.org/content/72/23_…

Pts undergoing clinically indicated elective coronary angiography for angina & had definite (typical) or probable (atypical) angina based on Rose angina questionnaire

391 pts ➡ angiography:
47% #INOCA
53% #CAD

3/7
✅ microvascular angina (MVA) = coronary microvascular dysfunction (#CMD) both endothelial independent (CFR/IMR) + endothelial dependent (ACh) (combined)

✅ vasospastic angina (VSA) = epicardial coronary endothelial dysfunction (ACh)

Read 8 tweets

@AHAMeetings

Heading to Philly for #AHA19?

Interested in learning about #CMD?

👇 Here is complete list of #CMD sessions @AHAMeetings 👇

Session #1
Diagnosis and Characterization of Coronary Microvascular Disease:
Role of Imaging

Nov 16, 7:15-8:30 AM

Session #2
Microvascular Coronary Disease: Update for the Practicing Clinician

Nov 16, 7:15-8:30 AM

Read 4 tweets

@escardio

A great move for patients with #CMD by @escardio

Definition, Dx & Rx are all addressed in new ESC 2019 Guidelines on Chronic Coronary Syndromes

✅ Invasive CFR/IMR: Class IIa rec
✅ Invasive Endo Fxn by ACh: Class IIb
✅ Non-invasive testing: Class IIb

escardio.org/Guidelines/Cli…

Definition of “Microvascular Angina” & how to distinguish between angina from #CMD & #CAD
👇

I personally avoid using this term because even when we establish Dx of #CMD, many pts have concomitant epicardial dz &/or Endo Dysfxn; so angina might be multifactorial or 2/2 other 2

@escardio

✅ @escardio recommend Rx for #CMD:
BBlockers
ACEi
Statins

✅ Our practice (in order):
BBlockers
Statins
ASA (if any CAD)
Nitrates
CCB
Ranolazine
ACEi

(no strong evidence for any of these meds)

@American_Heart

On behalf of @American_Heart CLCD/CVRI Cardiac Imaging Committee, I would like to invite you to join us for this great & unique educational symposium at #AHA19:

⚡️ Diagnosis & Characterization of #CMD: Role of Imaging ⚡️

@AHAMeetings @VTaqMD

@VTaqMD

We will have a great & diverse group of national & international experts (60% ♀+ cardiologists + radiologists) covering all imaging modalities: @VTaqMD @DorbalaSharmila @chiarabd Carl Pepine & Ornella Rimoldi. This is a unique opportunity for an imaging focused session on #CMD

Dr Pepine is teaching us about invasive imaging role in Dx of #CMD
#AHA19

@JACCJournals

⚡️ Coronary Microvascular Dysfunction is Associated with Significant Plaque Burden & Diffuse Epicardial Atherosclerotic Disease
@JACCJournals

interventions.onlinejacc.org/content/12/15/…
#JACCINT #CMD #CardioTwitter

Let's discuss this paper in 2 Tweets 👇

2/3
First demonstration that majority of pts with #CMD, but with no evidence of significant #CAD by angiography & #FFR, have significant plaque burden by #IVUS

3/3
Take home message:

✅ Large portion of patients with #CMD who have normal looking coronaries or mild #CAD on angiography, have indeed significant atherosclerosis & plaque burden on #IVUS

✅ These findings have important implications in management & prognosis in #CMD