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First, kudos to the Chinese authors doing this work & a shoutout to @edwardcholmes also involved
I already flagged this Wang et al. preprint yesterday but it is worth explaining its significance to both the #origins discussion and the related pandemic #prevention discussion
A🧵
I already flagged this Wang et al. preprint yesterday but it is worth explaining its significance to both the #origins discussion and the related pandemic #prevention discussion
A🧵
First: Origins
One thing that goes often down in all the noise surrounding #lableak is the fact that SARS-CoV-2, and actually all CoVs, possess #mosaic genomes.
This is because CoVs evolve not only through mutation but also through exchanging genetic elements with other CoVs
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One thing that goes often down in all the noise surrounding #lableak is the fact that SARS-CoV-2, and actually all CoVs, possess #mosaic genomes.
This is because CoVs evolve not only through mutation but also through exchanging genetic elements with other CoVs
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This exchange is called '#recombination'.
One can imagine CoV genomes like colorful Lego brick walls, and recombination as taking one brick from a different virus and putting it in the wall of another; changing the color while keeping roughly the function.
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One can imagine CoV genomes like colorful Lego brick walls, and recombination as taking one brick from a different virus and putting it in the wall of another; changing the color while keeping roughly the function.
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