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I'm excited to share my latest paper in @JASN_News on #complementbiology:
"Non-Invasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent
Imaging Probe."
pubmed.ncbi.nlm.nih.gov/36995143/
Time for a 🧵 & #tweetorial 👇
"Non-Invasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent
Imaging Probe."
pubmed.ncbi.nlm.nih.gov/36995143/
Time for a 🧵 & #tweetorial 👇
🧵(1/10): Histologic quantification of complement C3 deposits in kidney biopsies provides prognostic information in patients with:
- IgA nephropathy,
- ANCA-associated glomerulonephritis,
- Membranous nephropathy,
- Focal segmental glomerulosclerosis,
- Diabetic nephropathy.
- IgA nephropathy,
- ANCA-associated glomerulonephritis,
- Membranous nephropathy,
- Focal segmental glomerulosclerosis,
- Diabetic nephropathy.
🧵(2/10): As patients are not biopsied repeatedly (for obvious reasons!), histological examination only offers a single “snapshot” of a portion of a kidney at the time of sampling, which may not accurately represent the ongoing pathological process in both kidneys over time.
