Discover and read the best of Twitter Threads about #costeffectiveness

Most recents (5)

A thread. 1/11

An elected head of state is accountable, democratic, representative, cost effective. It provides stability, legitimacy, transparency, adaptability, and unity.

@RepublicStaff @GrahamSmith_ #NotMyKing
2/11

Accountability matters. An elected head of state is answerable to the people who voted them in. #accountability #democracy
3/11

Democracy is the bedrock of a free society. An elected head of state reflects the people's will, chosen through a fair and transparent process. #democracy #fairness
Read 11 tweets
Daily Bookmarks to GAVNet 07/01/2021 greeneracresvaluenetwork.wordpress.com/2021/07/01/dai…
Five ways to ensure flood-risk research helps the most vulnerable

nature.com/articles/d4158…

#research #ClimateChange #flooding #resilience #demographics
Neurons Act Not As Simple Logic Gates, But As Complex, Multi-Unit Processing Systems

resonancescience.org/blog/Neurons-A…

#neurons #dendrites #behavior #nodes #MultiUnit #ProcessingSystems
Read 8 tweets
#SIRT for advanced HCC has been recommended by @NICEComms. There may be some reasons for doing this but #costeffectiveness is not one of them. A short Tweetorial. @BSIR_News @cirsesociety @BASLedu nice.org.uk/news/article/h…
The relevant population here is people with advanced HCC. BCLC C, CP A, PS 1-2, unsuitable for conventional transarterial therapy (eg. portal vein thrombosis). These people have a dismal prognosis: most are dead within a year.
Treatment options are limited. Sorafenib is a protein kinase inhibitor and prolongs life slightly (vs best supportive care: SHARP trial) but at significant expense. It was originally rejected by NICE on this basis so Bayer applied via the Cancer Drugs fund (ie: reduced the cost).
Read 20 tweets
I'm now live tweeting from the #ISPOREurope session Much Ado About Little: Dealing with Limited RCT Evidence for Early HTA and Reimbursement Decisions with @MJSculpher, @SBujkiewicz, Eva Dietrich, Steven Palmer from @CHEyork, and @UweSiebert9
@MJSculpher starts by setting the context and introducing the speakers.
@UweSiebert9 is the 1st plenary speaker, on causal inference in #RCTs and #RWE
#ISPOREurope
When do we need causal inference methoss? when there's no randomisation; or the randomisation was broken (e.g. treatment switches)
Throughout his talk, Uwe will use the example of 2nd line treatment in women with ovarian cancer who progressed
#ISPOREurope
Read 48 tweets
Missed the panel “Value-Based Pricing and Market Allocative Efficiency: How Should Cost-Effectiveness Thresholds be Set to "Optimally" Distribute Value between Payers and Developers?” w @mikepaulden, @MBerdud & Laura Vallejo-Torres at #ISPOREurope?
ispor-europe2020.secure-platform.com/a/gallery/roun…
Laura starts with what her presentation will cover:
1-What is a #CostEffectiveness #Threshold for?
2-What should it reflect?
3-How to estimate it empirically?
4-What are the consequences of setting the decision threshold at != from empirical threshold?
#ISPOREurope
What is a #Threshold? It is to find out if an intervention generates more benefits gained than lost via the opportunity cost, AND/OR to identify a decision threshold that incorporates other policy objectives.
#ISPOREurope
Read 34 tweets

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