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O “tratamento precoce”, que envolve ministração de #hidroxicloroquina e #cloroquina, foi abandonado no Reino Unido, EUA, França, Itália, Alemanha, Espanha e Portugal, entre outros. Nenhum país avançado usa essas drogas contra a covid
A #HCQ e a #CQ foram abandonadas pela Agência Europeia de Medicamentos #EMA, Organização Panamericana de Saúde #OPAS e Organização Mundial de Saúde #OMS
Aqui, o estudo Coalizão COVID-19-Brasil, considerou-as ineficazes, formado por Hosp. Alb. Einstein, HCor, Hosp. Sírio-Libanês, Hosp. Moinhos de Vento (P. Alegre), Hosp. Osw. Cruz, Benef. Portug. de SP, Brazilian Clin. Research Institute e Rede Bras, de Pesq. Terapia Intensiva
🔥J'avais promis un thread sur ma présentation orale au congrès européen sur #COVID19 #ECCVID @ESCMID :
#Hydroxychloroquine: pros and cons
Congrès qui remplace @ECCMID annulé cette année
1/n
#Hydroxychloroquine: pros and cons
Congrès qui remplace @ECCMID annulé cette année
1/n
Le début de ce délire collectif autour #hydroxychloroquine peut être tracé au 25/02/2020 lorsqu'un microbiologiste français affirma
"une amélioration spectaculaire" ac #HCQ l''infection pulmonaire la plus facile à traiter" et a conseillé de courir en cherchesr d les pharmacies
"une amélioration spectaculaire" ac #HCQ l''infection pulmonaire la plus facile à traiter" et a conseillé de courir en cherchesr d les pharmacies
Ppl ask, why not try #Hydroxychlorquine and #Azithromycin for #SARSCov2 #COVID19. Here is some important info to know about the study sciencedirect.com/science/articl…
1. 20 HCQ pts (200 mg TID) & 16 controls with SARSCoV2
2. Pts w/ URTI, LRTI, or asx
3. 6 HCQ pts received Azithro x 5 d
1. 20 HCQ pts (200 mg TID) & 16 controls with SARSCoV2
2. Pts w/ URTI, LRTI, or asx
3. 6 HCQ pts received Azithro x 5 d
4. Pts received Azithro to prevent bacterial superinfxn
5. At day 6 post-inclusion 70% of HCQ pts were virologically cured vs 12.5% in control
6. At day 6 100% (6 pts ) with HCQ+Azithro were virologically cured vs 57.1% of HCQ only (14 pts) vs 12.5% in control (16 pts)
5. At day 6 post-inclusion 70% of HCQ pts were virologically cured vs 12.5% in control
6. At day 6 100% (6 pts ) with HCQ+Azithro were virologically cured vs 57.1% of HCQ only (14 pts) vs 12.5% in control (16 pts)
Although this data is potentially promising there are a few things to consider
1. This study is not powered for efficacy
2. Small sample size
3. No long term follow-up (although virologically cured unknown if it returned)
4. Unclear info on pt co-morbidities who received drugs
1. This study is not powered for efficacy
2. Small sample size
3. No long term follow-up (although virologically cured unknown if it returned)
4. Unclear info on pt co-morbidities who received drugs
