Discover and read the best of Twitter Threads about #cryptococcal

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#Cryptococcal Infection in #Hematologic #Malignancies and Hematopoietic Stem Cell Transplantation

Here we review crypto with attention to its background, epi, risk factors, presentations, diagnosis, treatment, & prevention in hematologic malignancies

pubmed.ncbi.nlm.nih.gov/32740974/
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At baseline, even prior to the start of immunosuppression, newly diagnosed patients with heme malignancies have cellular & humoral immune deficits with functional and absolute defects in granulocyte and lymphocyte function
that place patients at increased risk for infections
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Below is how crypto comes in from the environment. Note the very cool "Trojan horse" mechanism to get into the CNS!
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