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1/

As kidney replacement therapies (KRT) have become a strained and limited resource during the #COVID19 pandemic, here is a quick #tweetorial on how these treatments work:

What is the main mechanism by which clearance is achieved during intermittent #hemodialysis?
2/

KRT has 2 powers:
1⃣Clearance (removal of solutes, like potassium 🍌)
2⃣Volume removal 💧

...and it comes in 2 flavors:
1⃣Intermittent
2⃣Continuous
3/ How does the potassium go from 7.2 meq/L to 4 after an intermittent #hemodialysis (iHD) session?

Chemistry 101: DIFFUSION!

Solutes are cleared via diffusion as they move ⬇️ their concentration gradient across a SEMIPERMEABLE membrane

DOI: 10.1056/NEJMc1301071
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