Discover and read the best of Twitter Threads about #dermatopatologia
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#Melanoma: tumor agresivo de la piel. Frecuente en México en la región plantar. Mancha café a negro. Crece horizontal en un inicio y posteriormente invade. Se conoce como melanoma acral lentiginoso con crecimiento radial y vertical. Si está ulcerado, es peor el pronóstico (1). 
Si tiene mayor cantidad de células que invaden, espesor tumoral (Breslow) tiene posibilidad de entrar en vasos linfáticos, por ello es el factor pronóstico más importante. Debe incluirse en mm en el reporte histopatológico. Si es mayor de 0.8mm, cambia de estadio pT (2).
Es trascendental que se realicen revisiones anuales de toda la superficie de la piel. Que incluya que le revisen entre los dedos y si se ha visto lesiones en genitales, también deben ser evaluadas. Usamos el dermatoscopio para encontrar patrones incipientes. #dermatoscopia (3)
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Eosinophilic cytoplasmic bodies in melanocytes.
Perhaps one of the most overlooked findings in #dermpath -according to me-. I will show all the cases I’ve found since ~April 2020 (around 20 cases) and say a few words about #Gottliebbodies 👇🏼
#dermtwitter #PathTwitter
Eosinophilic cytoplasmic bodies in melanocytes.
Perhaps one of the most overlooked findings in #dermpath -according to me-. I will show all the cases I’ve found since ~April 2020 (around 20 cases) and say a few words about #Gottliebbodies 👇🏼
#dermtwitter #PathTwitter
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🔴Gottlieb bodies
I don’t spend much more time looking for them, I only search when I see sebocyte-like melanocytes (not that rare)
🏓 eosinophilic cytoplasmic body within an -usually-multinucleated vacuolated melanocyte
🏓 small incipient ones have basophilic appearance
🔴Gottlieb bodies
I don’t spend much more time looking for them, I only search when I see sebocyte-like melanocytes (not that rare)
🏓 eosinophilic cytoplasmic body within an -usually-multinucleated vacuolated melanocyte
🏓 small incipient ones have basophilic appearance
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🏓 larger fully developed ones have concentric lamination with eosinophilic staining
🏓 thought to represent degenerative changes in melanosomes, although this study doesn’t support such theory 👉🏼 pubmed.ncbi.nlm.nih.gov/21819442/
🏓 larger fully developed ones have concentric lamination with eosinophilic staining
🏓 thought to represent degenerative changes in melanosomes, although this study doesn’t support such theory 👉🏼 pubmed.ncbi.nlm.nih.gov/21819442/
