Discover and read the best of Twitter Threads about #disconn
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Out today @NeuroCellPress our work where we detail the wiring diagram of the mouse🐭default mode network (DMN)
👏👏Huge congrats & many thanks to @DrJigsaww @harrisjuliea and @AllenInstitute for leading the work & for such fruitful collaboration
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cell.com/neuron/fulltex…
👏👏Huge congrats & many thanks to @DrJigsaww @harrisjuliea and @AllenInstitute for leading the work & for such fruitful collaboration
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cell.com/neuron/fulltex…
Reposting the original thread below with summary of main findings and explanation of how these results may affect/guide your research
@NeuroCellPress version contains streamlined writing and more retro-seq data so all original @biorxive results hold
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@NeuroCellPress version contains streamlined writing and more retro-seq data so all original @biorxive results hold
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And of course very grateful to funding agencies who supported this work (@ERC_Research #Disconn @IITalk ) and people in the lab who contributed to this research @adliska @ColettaLudovico 👏
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**New preprint from the lab**
Regional, layer and cell-class specific connectivity of the mouse default mode network tinyurl.com/yddanw5w
Conceived & majestically led by @DrJigsaww @harrisjuliea @AllenInstitute
Thread covering DMN basics + implications of findings
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Regional, layer and cell-class specific connectivity of the mouse default mode network tinyurl.com/yddanw5w
Conceived & majestically led by @DrJigsaww @harrisjuliea @AllenInstitute
Thread covering DMN basics + implications of findings
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What is the Default Mode Network (DMN)?
👉Network identified in human PET/fMRI studies
👉Active and strongly synchronized during rest
👉Desynchronized by goal-oriented tasks
👉Encompasses associative cortices - Prefrontal, Cingulate, Retrosplenial, Parietal, Temporal
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👉Network identified in human PET/fMRI studies
👉Active and strongly synchronized during rest
👉Desynchronized by goal-oriented tasks
👉Encompasses associative cortices - Prefrontal, Cingulate, Retrosplenial, Parietal, Temporal
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Why study the DMN?
👉Most prominent large-scale network of human brain
👉Pivotal substrate for higher-order cognitive and social functions
👉Key point of vulnerability for autism, schizophrenia, Alzhemier's and other brain disorders (seminal feature review below)
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👉Most prominent large-scale network of human brain
👉Pivotal substrate for higher-order cognitive and social functions
👉Key point of vulnerability for autism, schizophrenia, Alzhemier's and other brain disorders (seminal feature review below)
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