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As promised, here is a #tweetorial on spatially-fractionated radiotherapy aka Lattice aka GRID.
If you missed the #CTOS2019 talk by @Notorious_RBE, this one is for you!
If you missed the #CTOS2019 talk by @Notorious_RBE, this one is for you!
Spatial fractionation aims to intentionally deliver heterogeneous dose: alternating “hot” and “cold” areas with a differential of 30-100% Rx.
Thats right: you want 30% cold spots in tumor. (👇 #MedPhys reaction).
Thats right: you want 30% cold spots in tumor. (👇 #MedPhys reaction).
It seems crazy, but it is associated with excellent response and limited toxicity. Per reports. That are retrospective.
Dramatic response in rads refractory sarcoma: link.springer.com/article/10.100…
Case series of 71 palliative patients: ncbi.nlm.nih.gov/pubmed/1052442…
Dramatic response in rads refractory sarcoma: link.springer.com/article/10.100…
Case series of 71 palliative patients: ncbi.nlm.nih.gov/pubmed/1052442…
