Discover and read the best of Twitter Threads about #drugdelivery

Most recents (4)

#MyFirstChemSci 🙌🏼
Are you an antibiotic targeting RNA-P? You just got an upgrade! We used the microbial iron transport machinery to enhance potency and improve accumulation into bacteria, where cleavable linkers release. @ChemicalScience

A 🧵: (1|n) Image
We found a way to enhance the potency of antibiotics targeting RNAP, rifamycins but also Corallopyronin A & Sorangicin A, by exploiting microbial iron transport to improve drug translocation across bacterial membranes using bacterial iron chelators- #siderophores. (2|n) Image
Gram-negative bacteria pose a unique challenge, due to their double membrane structure for antibiotic uptake e.g. for RNA-P inhibitors needing to reach the cytosol. But with innovative, targets approaches we can enhance their antimicrobial activity and overcome this hurdle. (3|n)
Read 13 tweets
Daily Bookmarks to GAVNet 12/15/2021…
Well-Structured German Study Shows No Deaths among Healthy German Kids Ages 5 to 11 ⋆ Brownstone Institute…

#MedicalStudy, #germany, #COVID19, #mortality, #children, #SchoolClosures
Fast superhighway through the Solar System discovered - Big Think…

#ArchesOfChaos, #SpaceTravel, #SolarSystem, ScientificDiscovery
Read 20 tweets
Read 210 tweets
"Treatment of Bacterial Infections with Porous Silicon Nanoparticles" by Prof Michael Sailor, University of California, San Diego.
#Seminar @MIPS_Australia #NanoTech #Science
Michael is doing research in using porous silicon particles for drug delivery.
#PharmSci #DrugDelivery
Runs a summer school for teaching people to use silicon nanotechnology.
Read 17 tweets

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