Discover and read the best of Twitter Threads about #drugrepositioning
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Thrilled to share our work on #covid19 #drugrepositioning, one of the first computational work with experimental validation. Though we need to further troubleshoot the cytotoxicity, since we started in late Jan, cannot wait to share what we have learned.
biorxiv.org/content/10.110…
biorxiv.org/content/10.110…
1. Some anti-cancer drugs may be effective, but in general, they are toxic. may not appropriate for weak patients.
2. Anti-parasite drugs like #ivermectin, #niclosamide showed nice in vitro activity, but they are not soluble, challenging to deliver into the infected cells.
