Discover and read the best of Twitter Threads about #drugsafety
Most recents (7)
Let's uncover something with #SubstanceSaturdays
1/ #Xylazine is a sedative and analgesic drug that is commonly used in veterinary medicine to sedate and immobilize animals. It is also used as an anesthetic in laboratory animals and as a tranquilizer in horse racing.
1/ #Xylazine is a sedative and analgesic drug that is commonly used in veterinary medicine to sedate and immobilize animals. It is also used as an anesthetic in laboratory animals and as a tranquilizer in horse racing.
2/ Xylazine is a Schedule III controlled substance under the United Nations Convention on Psychotropic Substances, meaning that it has a potential for abuse and dependence, and it should be used under strict medical supervision. One of its nicknames is "#tranq".
3/ Unfortunately, Xylazine is being used to contaminate the drug supply, and it is being sold as a street drug. This is a dangerous practice as Xylazine can cause serious side effects, including respiratory and cardiovascular depression, and even death in high doses.
🧵 How well do you know your dopamine antagonists? 💊💊
1/ Using these drugs safely requires that clinicians & patients appreciate their important #AdverseEffects, which are not always well understood
👉🏽ti.ubc.ca/letter139
#MedEd #prescribing #deprescribing #medsafety
1/ Using these drugs safely requires that clinicians & patients appreciate their important #AdverseEffects, which are not always well understood
👉🏽ti.ubc.ca/letter139
#MedEd #prescribing #deprescribing #medsafety
2/ #AdverseEffects may include:
⚠️ Drug-induced #Parkinsonism
-↘️ or slowed movements, rigidity/tremor/unsteadiness, facial expression loss
⚠️ #Akathisia
-intense internal restlessness or desire to move (which may be mistaken for anxiety)
👉🏽Pt videos: ti.ubc.ca/letter139
⚠️ Drug-induced #Parkinsonism
-↘️ or slowed movements, rigidity/tremor/unsteadiness, facial expression loss
⚠️ #Akathisia
-intense internal restlessness or desire to move (which may be mistaken for anxiety)
👉🏽Pt videos: ti.ubc.ca/letter139
3/ #AdverseEffects may include:
⚠️Acute dystonic reaction
-sudden, involuntary, often painful muscle spasm
⚠️Dyskinesia
-repetitive, involuntary movements...can be associated with cognitive decline
👉🏽Pt experience videos: ti.ubc.ca/letter139
#MedEd #ptsafety #drugsafety
⚠️Acute dystonic reaction
-sudden, involuntary, often painful muscle spasm
⚠️Dyskinesia
-repetitive, involuntary movements...can be associated with cognitive decline
👉🏽Pt experience videos: ti.ubc.ca/letter139
#MedEd #ptsafety #drugsafety
THREAD:5⃣things to know from 5 recent TI Therapeutics Letters👩🏽🔬
1/5: How to choose a good #mirtazapine dose? 🤔
Mirtazapine has a dose response 💊for harm but NOT for efficacy: harm ↗️ after 30mg/day but efficacy doesn't: bit.ly/361LU9E
#MedEd #deprescribing #ptsafety
1/5: How to choose a good #mirtazapine dose? 🤔
Mirtazapine has a dose response 💊for harm but NOT for efficacy: harm ↗️ after 30mg/day but efficacy doesn't: bit.ly/361LU9E
#MedEd #deprescribing #ptsafety
2/5: Want to learn about recent @GovCanHealth #medsafety or international warnings for medications?
Read our Therapeutics Letter on international drug safety advisories: bit.ly/3wc0ar8 ⚠️ 💊
#drugsafety #SegPac #ptsafety
Read our Therapeutics Letter on international drug safety advisories: bit.ly/3wc0ar8 ⚠️ 💊
#drugsafety #SegPac #ptsafety
3/5: Do you like receiving feedback on your #prescribing?👩🏽⚕️💊
Read about Personal Prescribing Portraits: bit.ly/3hkf8WO
#MedEd #deprescribing
Read about Personal Prescribing Portraits: bit.ly/3hkf8WO
#MedEd #deprescribing
THREAD - What if we could track and record repeat Adverse Drug Events? 🤔 💊
1/6: Register for our May 12 #BestEvidence webinar, as @corinne_hohl talks about Assessing the Impact of Information Continuity on Health Outcomes: bit.ly/3ap4FGO #MedEd
1/6: Register for our May 12 #BestEvidence webinar, as @corinne_hohl talks about Assessing the Impact of Information Continuity on Health Outcomes: bit.ly/3ap4FGO #MedEd
2/6: Why do Adverse Drug Events (ADEs) matter?
Each year in British Columbia, ADEs account for:
👉240,000 emergency dept (ED) visits
👉480,000 days in hospital
👉approx. 1 in 9 adult ED visits
More here: bit.ly/2Q7UGi8
#drugsafety #ptsafety #MedEd
Each year in British Columbia, ADEs account for:
👉240,000 emergency dept (ED) visits
👉480,000 days in hospital
👉approx. 1 in 9 adult ED visits
More here: bit.ly/2Q7UGi8
#drugsafety #ptsafety #MedEd
3/6: In Canada, adverse drug events 💊 cause or contribute to almost 2⃣million emergency department visits annually 😯 🆘
See publication list here: actionade.org/referenced-art…
#MedEd #ptsafety #prescribing
See publication list here: actionade.org/referenced-art…
#MedEd #ptsafety #prescribing
THREAD: Dr. John Mandrola: “The more you see, the harder the medicine gets”
1/7 Some new views on legacy prescriptions: Beta-blockers, ASA & #statins by Dr. John Mandrola
(based on @drjohnm presentation hosted by @drug_evidence Oct 17, 2020: bit.ly/32fsPiA)
#MedED
1/7 Some new views on legacy prescriptions: Beta-blockers, ASA & #statins by Dr. John Mandrola
(based on @drjohnm presentation hosted by @drug_evidence Oct 17, 2020: bit.ly/32fsPiA)
#MedED
2/7 Example 1: Beta blockers in heart failure 💊♥️
Observational studies suggest beta-blockers for heart failure tx beyond 3 years are NOT associated with beneficial outcomes 😯
These findings challenge current recommendations: bit.ly/3acX9P7
#MedEd #deprescribing
Observational studies suggest beta-blockers for heart failure tx beyond 3 years are NOT associated with beneficial outcomes 😯
These findings challenge current recommendations: bit.ly/3acX9P7
#MedEd #deprescribing
3/7 Ex. 2: How about beta blockers to treat MIs, looking at research from pre-reperfusion & reperfusion eras?
Large meta-analysis of about 60 trials, with > than 100,000 pts found NO difference from using beta blockers in the reperfusion era: bit.ly/3dfvn6u
#MedEd
Large meta-analysis of about 60 trials, with > than 100,000 pts found NO difference from using beta blockers in the reperfusion era: bit.ly/3dfvn6u
#MedEd
Excited for Priya Bahri’s plenary session on #scicomm at #ICPE20 #RxEpi starting at 11:15am ET today
#pharmacoepidemiology @ISPE_Exchange
#pharmacoepidemiology @ISPE_Exchange
Here we go! #icpe2020
"Is silence better than getting it wrong?" when it comes to emerging medication safety issues for patients - Priya Bahri asks of #drugsafety at #ICPE20
A🧵1/6
I am an infection doctor & scientist. My PhD is on unwanted effects of #antimalarial medicines, like chloroquine, on the heart. In overdose (taken too often or in excessive amounts) or in unapproved combinations, chloroquine, hydroxychloroquine & azithromycin kill #COVID19
I am an infection doctor & scientist. My PhD is on unwanted effects of #antimalarial medicines, like chloroquine, on the heart. In overdose (taken too often or in excessive amounts) or in unapproved combinations, chloroquine, hydroxychloroquine & azithromycin kill #COVID19
2/6
Important to use drugs at the right doses at which they have been properly evaluated, and as recommended by international guidelines from expert physicians and pharmacologists like @WHO. Antimalarials are typically dosed by body weight in kg.
who.int/docs/default-s…
Important to use drugs at the right doses at which they have been properly evaluated, and as recommended by international guidelines from expert physicians and pharmacologists like @WHO. Antimalarials are typically dosed by body weight in kg.
who.int/docs/default-s…
3/6
From global evidence review @WHO #malaria #drugsafety, co-chairs Prof Josep Brugada @hospitalclinic & Prof Sir Nick White @TropMedOxford, rapporteur @xhschan:
Chloroquine & hydroxychloroquine associated with sudden death in overdose @UMCGlobalSafety
who.int/malaria/mpac/m…
From global evidence review @WHO #malaria #drugsafety, co-chairs Prof Josep Brugada @hospitalclinic & Prof Sir Nick White @TropMedOxford, rapporteur @xhschan:
Chloroquine & hydroxychloroquine associated with sudden death in overdose @UMCGlobalSafety
who.int/malaria/mpac/m…
