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Welcome to a new @MayoMN_IMRES #EBM #Tweetorial Series!
Content is brought to you by @CourtHarrisMD @Jaegermeister58 & @ColinWestMDPhD. Our purpose: educate on confusing #EBM topics! Engage with us & RT if you find this helpful!
Topic: Clinical vs statistical significance
Welcome to a new @MayoMN_IMRES #EBM #Tweetorial Series!
Content is brought to you by @CourtHarrisMD @Jaegermeister58 & @ColinWestMDPhD. Our purpose: educate on confusing #EBM topics! Engage with us & RT if you find this helpful!
Topic: Clinical vs statistical significance
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Let’s get our definitions straight first!
➡️Clinical significance: the importance of the observed effect in practice (i.e., is the magnitude of the effect large enough to affect clinical care)
Let’s get our definitions straight first!
➡️Clinical significance: the importance of the observed effect in practice (i.e., is the magnitude of the effect large enough to affect clinical care)
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➡️Statistical significance: p < 0.05 (commonly). This does NOT mean the probability the conclusion is false is <5%!
See this article from @Amstatnews on guiding principles for p-value use (this is a game changer article people): amstat.tandfonline.com/doi/full/10.10…
➡️Statistical significance: p < 0.05 (commonly). This does NOT mean the probability the conclusion is false is <5%!
See this article from @Amstatnews on guiding principles for p-value use (this is a game changer article people): amstat.tandfonline.com/doi/full/10.10…
