Discover and read the best of Twitter Threads about #ecoli

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đŸ§” "A #biologist's perspective of #process and #pattern in #innovation"
by SFI External Professor @HochTwit

Starting in just a few minutes on our YouTube channel.

Follow this thread for select slides and quotations...
youtube.com/user/santafein
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"I'm not going to pretend there's a unified theory of #innovation, and I'm going to explain why."

We begin with a tale of #Minitel: the original, now-extinct French "Web"...and then back further to #ARPANet...and then to theoretical precursors.


@HochTwit ImageImageImage
"There is no first-principles definition for #innovation."

"How could a company start with selling books online when people want to see a book in person and look through it? Nonetheless, @amazon survived..."

Before Amazon, Books.com on TelNet, later bought by B&N ImageImageImageImage
Read 15 tweets
Pourquoi l’ingestion de pizzas #buitoni contaminĂ©es par une bacterie peut entrainer une atteinte des reins comme l’ont prĂ©sentĂ© plusieurs dizaines d’enfants et d’adolescents
 Petit thread grand public
La maladie responsable s’appelle le syndrome hĂ©molytique et urĂ©mique ou SHU. Son nom vient de sa description dans les annĂ©es 50 oĂč lors d’une Ă©pidĂ©mie de gastro, des dizaines d’enfants avaient prĂ©sentĂ© un tableau associant un excĂšs d’urĂ©e et une destruction de globules rouge
Certaines bactĂ©ries sont capables de fabriquer des protĂ©ines qui vont leur donner des propriĂ©tĂ©s augmentant leur potentiel d’atteinte. On appelle ça la virulence. Parmi ces protĂ©ines, on identifie les toxinques qui sont capable de dĂ©truire des structures cellulaires
Read 17 tweets
#Haemolysis data indicates that #disruption of host cell #membranes by rotating #flagella is physically possible, despite what previously published measurements with firing gold nanobeads at tissue cultures tells us.

[Pls read the paper for the more complex story with E.coli]
But what if #flagella did penetrate host cell #membranes? What might that mean?
Well, in vitro at least, #Ecoli and #Salmonella #flagella can enhance #actin #polymerization rates. Interactions with #Cofilin-1 (CFL) had an additive effect... Actin polymerisation rates with flagella from E. coli (H6, H
Read 8 tweets
8 years since the first manuscript draft but it's finally here!

The interaction of #Ecoli O157 :H7 and #Salmonella Typhimurium #flagella with host cell #membranes and cytoskeletal components | #Microbiology #Pathogenesis #Thread

microbiologyresearch.org/content/journa

@strain9000 @ArielBlocker @MicrobioSoc This all started many 🌑🌒🌓🌔🌕🌖🌗🌘🌑 ago...

Jo Elvidge and I were looking at the role of #flagella in early infection of #Salmonella and #Ecoli in relevant animal tissue models (🐖🐄)

We spotted what looked like very intimate adherence... E.coli O157:H7 on Bovine terminal rectal cellsSalmonella Typhimurium on porcine epithelial cells
It was a toughie to quantify back then with the tools we had, but every time we looked, we saw it đŸ€“
Read 9 tweets
AprÚs les "Romaine Outbreaks" de 2018 et 2019, verra-t-on encore du bétail non loin des cultures de salades aux US ?
#EColi âŹ‡ïž
Suite au rapport de la FDA qui met en évidence la proximité du bétail ds la contamination, la California Leafy Green Marketing Association met en place un comité "des terres adjacentes"
foodsafetynews.com/2020/07/pews-e

@CptPhosphore si utilisation d'un "engrais humain" comme tu le prĂ©conises, on est d'accord que potentiellement on peut se retrouver avec le mĂȘme problĂšme ?
Read 4 tweets

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