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F/U recent ACG-VGR "High-Resolution Manometry: Thinking beyond the Chicago Classification", @JPandolfinoMD answered Qs that u can encounter when reading #HRM routinely. Q&A posted on ACG circle @AmCollegeGastro. For #GITwitter who may not have access. Here are some (summarized)
1/
Q: How do u explain achalasia w/ NORMAL IRP. Isn't achalasia characterized by loss of nerves at LES=abnormal IRP?
Dr. Pandolfino: A few explanations-If u start w/ basal LES pressure of 12mmHg- u will naturally have an IRP < 15. Another issue is that HRM catheter...
2/
...only assesses contact & the mechanics of LES can be such that there is minimal contact-even though there is no relaxation. The HRM catheter is not the best tool to assess relaxation- u need strain measures in the muscle & need to see lengthening in the muscle...
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