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BREAKING: Risk of #COVID19 hospitalization in 77,590 persons with #HIV by antiretroviral type:
TDF/FTC: 10.5
TAF/FTC: 20.3
ABC/3TC: 23.4
Other: 20.0
per 10,000 (Febr-April 2020)

WANTED: Randomized trials of TDF/FTC (Tenofovir/Emtricitabine)

doi.org/10.7326/M20-36… Image
That is, individuals on TDF/FTC had about half the risk of #COVID19 hospitalization than those on TAF/FTC or ABC/3TC.

Rate ratio 0.53 (95% CI 0.29, 0.95)
journals.lww.com/epidem/Citatio…
Any reasonable person should be concerned about confounding, so we did the following 3 things
👇 Image
1) We restricted the analysis to individuals younger than 60 years, who have the lowest prevalence of comorbidities.

Rate ratio of #COVID19 hospitalization: 0.55 (0.29–1.04) for TDF/FTC compared with TAF/FTC.

Confounding by comorbidities appears less likely now.
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