Discover and read the best of Twitter Threads about #equivalent

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National DNA Day:

🧬April 25

🧬Commemorates the day in 1953 when Watson, Crick, Wilkins, Franklin and colleagues published papers in the journal @nature on the structure of DNA

🧬Also commemorates the completion of the Human Genome Project in April 2003, took 13 years

#DNADay
DNA Double Helix:

🧬The two #DNA strands are reverse-complements

🧬Reading one strand in #reverse order and exchanging each base with its #complement gives the other strand

🧬A and T are complements, C and G are complements

DNA Sequence: AGTAGCAT
Reverse-Complement: ATGCTACT
In #Each DNA Strand:

🧬Pull the #DNA double helix apart, leaving the two single DNA strands

🧬The population (or occurrence) of every DNA sequence in that single-strand is #equivalent to the population of its reverse-complement DNA sequence in that same single-strand

#Genomics
Read 5 tweets
Data Needs A Home:

🧬The population of every DNA word is equivalent to the population of its reverse-complement DNA word in the SINGLE-STRANDED human genome

🧬Population count of 1.4 trillion DNA words

🧬Does anyone want a copy of this data before files are deleted?

#Genomics
Can You Use This #Data?

🧬Demonstrates the inherent inversion symmetry structure for all DNA elements in the single-stranded genome

🧬Demonstrates the absence of analog symmetries between reverse pairs and complement pairs of DNA elements

#BigData
🔂

👉cell.com/iscience/fullt…
Do You Know Anyone 🏷 Who Can Use This Data?

🧬The number of times every #DNA element (1-nt to 20-nt) occurs in the single-stranded genome

🧬This inversion symmetry structure is also maintained at the level of each individual #chromosome, except chromosome M (mitochondrial DNA)
Read 6 tweets

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