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Hugely excited to share our paper (@mannlab) out in #ERJ (@ERSpublications) showing monocyte immune profiles identify unique features of #longCOVID symptoms and define acute hospitalised #COVID19 severity. Interested? 🧵of key messages for scientists, clinicians and patients 1/10
We studied monocyte immune profiles in acute hospitalised COVID19, and at up to 9 months post-COVID19. Healthy individuals, convalescent RSV/influenza, and progressive fibrosing ILD were used as controls (2/10)
Acute #COVID19 CXCR2 and COX-2 expression decreased with severity whilst adhesion (CD62L) and migration (ITGb7) markers increased. Other adhesion and migration molecules (notably PSGL1 and CXCR6) increased across severity. (3/10)
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