Discover and read the best of Twitter Threads about #evodevo

Most recents (8)

1. In evolutionary psychology (EP), what is genetically coded?

* Behavior? No
* Psychological mechanisms or modules? No
* Developmental programs? Yes!

A brief tweetorial 🧵 Homologous hox genes in suc...
2. Humans start off as a single fertilized cell that, over 9 months, develops into an intricately structured, 2 trillion cell infant, and over 20 years, into a 30 trillion cell adult.
nature.com/articles/s4158…
3. 170 billion of those cells constitute the brain

Human brain organogenesis: Toward a cellular understanding of development and disease sciencedirect.com/science/articl… Key human brain development...
Read 18 tweets
Happy our review on the lateral plate mesoderm is out @Dev_journal, with @karin_prummel & @Susan81643382 (open access).

Our first attempt at reviewing the fascinating, wacky, complex biology as Development at a Glance with poster!
#devbio #evodevo
dev.biologists.org/content/147/12… Image
The LPM forms several central cell fates and organ systems, including the heart, endothelium, blood, limb connective tissue, and much more.

This seemingly weird combo of downstream fates seems unrelated the adult body - but they all share a common LPM origin!
Our review now attempts to summarize how LPM's development (and possible evolution) ties these diverse downstream fates together.

We also discuss that not all "mesoderm" is equal:
the LPM forms as dedicated mesendoderm lineage early on, both in development and evolution.🧬🧬🧬
Read 8 tweets
Working on lectures for #AnimalBehavior. Today's topics - #learning & #EvoDevo of behavior.

I knew #crows were smart AF, but then I found this @PLOS paper on these fancy #reptiles figuring out how water displacement works (journals.plos.org/plosone/articl…)
The article has this awesome supplementary video on YouTube ()

I laughed out loud🤣at the #crow in the U-tube experimental trial! This is so cool.

#AnimalBehavior
#onlinelearning
Not that I need to say it, but designing & creating a 6-week course for summer is BRUTAL. Not to mention one for #onlinelearning

But this kind of awesome #AnimalBehavior #science makes it a tiny bit easier to tackle.
Read 3 tweets
Just out in Biology & Philosophy: “Beyond networks: mechanism and process in evo-devo,” the first publication from a wonderfully productive collaboration with philosopher James DiFrisco.

researchgate.net/publication/33…

link.springer.com/article/10.100…

#philsci #evodevo
This paper should be of interest well beyond the field of #evodevo. Our argument applies equally to network-based explanations in systems biology. /1
The main point is that static representations of regulatory networks do *not* provide causal-mechanistic explanations for metabolic, physiological, developmental, behavioural, or other complex phenotypes. /2
Read 11 tweets
A special symposium #EvoDevo19 honored Dr. GĂĽnter Wagner for his leadership & service to our profession, especially as Journal of Experimental Zoology editor-in-chief . To show our appreciate of his contributions to #evodevo, here are some books & papers we like!
Landmark paper with Lee Altenberg in 1996 in Evolution is a must read!

Complex Adaptations and the Evolution of Evolvability
jstor.org/stable/2410639 (read online free)
FYI, Laura Nuño de la Rosa used a co-citation analysis to show that Wagner & Altenberg (1996), Houle (1992), and Kirschner & Gerhart (1998), were the three key papers that made "evolvability" into a "true research front"

Computing the Extended Synthesis: onlinelibrary.wiley.com/doi/full/10.10…
Read 13 tweets
Digesting lunch with “Extending developmental approaches to evolution: chance, plasticity, and environmental stress in evolvability.” #ISHPSSB19
1. Laura Nuño de la Rosa presents a propensity-based interpretation of how variability leads to evolvability: propensities to generate adaptive variation are structure through the g-p map and evolve. #evodevo
2. Cristina Villegas argues that development fits into a causal theory of evolution through developmental channeling, which creates a dappled (irregularly accessible) structure of morphospace. #evodevo
Read 4 tweets
Network modularity: structure does not equal function. I am very proud and excited about our new paper on dynamic modules, just out in @eLife! @BertaVerd elifesciences.org/articles/42832 #evodevo

Tl;dr tweet summary follows...👇🏻
@eLife @BertaVerd Systems biology aims to understand function and evolution of complex regulatory networks. This requires hierarchical decomposition into manageable and intelligible subsystems with delimited and discernible functions (functional modules). /1
@eLife @BertaVerd Functional decomposition of complex networks usually relies on partitioning the graph representing the network into simple subgraphs. Subsystems are defined in terms of network structure/topology (structural modules). /2
Read 23 tweets
#COSB_seminar @univienna Nicolas Gompel talks about regulatory evolution underlying wing patterning in insects. #evodevo Image
Gompel argues, using evidence from the yellow wing spot enhancer, that modular “minimal enhancers” may capture a qualitative pattern but not the quantitative pattern driven by the endogenous gene.
Enhancer modularity is a matter of degree, as binding sites outside the “minimal enhancer” contribute to the pattern, also contributing to other functions, like ubiquitous expression across the wing blade.
Read 5 tweets

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