Discover and read the best of Twitter Threads about #exdifferentiation
Most recents (1)
1/5 Fascinating work from Jae-Hyun Yang and colleagues on #mammalian #aging, published in Cell...
An abstract thread 🧵...
"All living things experience an increase in #entropy, manifested as a loss of #genetic and #epigenetic information."
cell.com/cell/fulltext/…
An abstract thread 🧵...
"All living things experience an increase in #entropy, manifested as a loss of #genetic and #epigenetic information."
cell.com/cell/fulltext/…
2/5 "In #yeast, #epigenetic information is lost over time due to the relocalization of #chromatin-modifying proteins to #DNA breaks, causing cells to lose their identity, a hallmark of yeast #aging."
3/5 "Using a system called “#ICE” (#inducible changes to the #epigenome), we find that the act of faithful #DNA #repair advances aging at #physiological, #cognitive, and #molecular #levels, including #erosion of the #epigenetic #landscape,..."
