Discover and read the best of Twitter Threads about #fightcovid

Most recents (5)

Super exciting and very laborious new study @berlinnovation (with @UKL_Leipzig and us @dkfz) on the question of why #children are so much less likely to develop severe #COVID19 than adults! Central point (experts may smile tiredly 😉): #interferon!
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nature.com/articles/s4158…
Our colleagues in Berlin studied cells in nasal swabs from a total of >80 people (single cell RNA sequencing, #scRNASeq)– 42 children and 44 adults, half of each were healthy and half #SARSCoV2-infected. What we found was intriguing: already in…
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... healthy children, the cells of the nasal mucosa (epithelial and immune cells) were already on heightened alert! I.e. they had a significantly higher expression of the sensor system for #virus infection (esp. MDA5 and RIG-I). @VladimirMagalh in our lab was able to show ...
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Read 9 tweets
Wirklich super spannende und sehr aufwändige neue Studie @berlinnovation (zusammen mit @UKL_Leipzig und uns @DKFZ) zur Frage, weshalb #Kinder so viel seltener schwer an #COVID19 erkranken als Erwachsene! Zentraler Punkt (der Fachmann wird müde lächeln 😉): #Interferon!
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Die Berliner Kollegen haben die Zellen im Nasenabstrich von insgesamt >80 Menschen untersucht (Einzelzell-RNA-Sequenzierung, #scRNASeq)– 42 Kinder und 44 Erwachsene, je die Hälfte gesund und die andere #SARSCoV2-infiziert. Was wir fanden war faszinierend: bereits bei…
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… gesunden Kindern waren die Zellen der Nasenschleimhaut (Epithel- und Immunzellen) bereits in erhöhter Alarmbereitschaft! D.h. sie hatten ein deutlich ausgeprägteres Sensorsystem für #Virus-Infektion (v.a. MDA5 und RIG-I). @VladimirMagalh in unserem Labor konnte zeigen, …
3/7
Read 10 tweets
So my sister has been working round the clock to help people prevent and cure from COVID at home with her generous intiatives like providing 𝗙𝗥𝗘𝗘 fitness (Yoga, diet, nutrition, answering covid queries). Today, I happened to join in her class, and I was totally
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Totally blown away with the quality of coaching she is giving. Not because she is my sis but bcs she is really teaching world class stuff there with so much fun that if you were like me who think "yoga is boring", you will go like "who said?"
I asked her @YogaGirlHeena, why
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I asked her "why 𝗙𝗥𝗘𝗘"? This is worth lacs of coaching and the compassion you pour in to help people cure
(Along with great experience in yoga, she is also one among the toppers in Yoga sports coaching from NSNIS, popular for preparing bright minds to 𝗢𝗹𝘆𝗺𝗽𝗶𝗰𝘀)
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Read 8 tweets
1/ Many discussions on #SARSCoV2 / #COVID19 are quite abstract and focus on infection routes and epidemiology. Further, we often get the question "Can you detect actual #Coronavirus at all, or only 'gene snippets' by this PCR?“ Here come some information, now in English!
2/ The novel #Coronavirus has been isolated countless times from patients, incl. "BavPat1/2020", from one of the first patients in Bavaria, by the team around @c_drosten. Several isolates can be ordered from bio material repositories, e.g. european-virus-archive.com/evag-portal/vi…
3/ The genomes of these isolated and laboratory grown viruses were sequenced, as were thousands of samples from patients around the globe: nextstrain.org/ncov/global. By #sequencing it is possible to clearly identify which exact virus is present. By the way...
Read 27 tweets
1/ Viele Diskussionen um #SARSCoV2 / #COVID19 sind recht abstrakt und drehen sich v.a. um Infektionsrouten und die Epidemiologie. Außerdem immer wieder die Frage „Könnt ihr das #Coronavirus überhaupt nachweisen, oder nur ‘Genschnipsel‘ mit der ‘Drosten-PCR’?“ Hier ein paar Infos!
2/ Das #Coronavirus wurde unzählige mal aus Patienten isoliert, u.a. vom Team um @c_drosten („BavPat1/2020“, aus einem der ersten Patienten in Bayern isoliert). Etliche Isolate kann man (mit entspr. Genehmigung) z.B. beim European Virus Archive bestellen european-virus-archive.com/evag-portal/vi…
3/ Die Genome dieser isolierten und im Labor angezüchteten Viren wurden sequenziert, ebenso wie tausende Proben aus Patienten rund um den Globus: nextstrain.org/ncov/global. Durch #Sequenzierung ist ganz eindeutig nachzuweisen, welches Virus vorliegt. Übrigens…4/
Read 28 tweets

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