Discover and read the best of Twitter Threads about #flagella

Most recents (3)

#Haemolysis data indicates that #disruption of host cell #membranes by rotating #flagella is physically possible, despite what previously published measurements with firing gold nanobeads at tissue cultures tells us.

[Pls read the paper for the more complex story with E.coli]
But what if #flagella did penetrate host cell #membranes? What might that mean?
Well, in vitro at least, #Ecoli and #Salmonella #flagella can enhance #actin #polymerization rates. Interactions with #Cofilin-1 (CFL) had an additive effect... Actin polymerisation rates with flagella from E. coli (H6, H
Read 8 tweets
8 years since the first manuscript draft but it's finally here!

The interaction of #Ecoli O157 :H7 and #Salmonella Typhimurium #flagella with host cell #membranes and cytoskeletal components | #Microbiology #Pathogenesis #Thread

microbiologyresearch.org/content/journa…
@strain9000 @ArielBlocker @MicrobioSoc This all started many 🌑🌒🌓🌔🌕🌖🌗🌘🌑 ago...

Jo Elvidge and I were looking at the role of #flagella in early infection of #Salmonella and #Ecoli in relevant animal tissue models (🐖🐄)

We spotted what looked like very intimate adherence... E.coli O157:H7 on Bovine terminal rectal cellsSalmonella Typhimurium on porcine epithelial cells
It was a toughie to quantify back then with the tools we had, but every time we looked, we saw it 🤓
Read 9 tweets
It’s out! Our paper “Marine Sediments Illuminate Chlamydiae Diversity and Evolution” was published in @CurrentBiology today! Below a thread with major highlights 1/11

cell.com/current-biolog…
Big thanks to fantastic co-authors! Celebrating with @DanielTamarit, @eme_laura, @cstairs, @JoranMartijn, @hfixou, Steffen Jørgensen, @anjspa1, and @Ettema_lab. Work done @MolEvoUpp, @MIB_WUR, and @uibgeo.

For a visual summary, check out our graphical abstract 2/11
In short: Phylogenetically diverse new lineages of #Chlamydiae (a bacterial phylum which includes the pathogen #Chlamydia) are abundant and active in deep #anoxic #marine #sediments taken from near Loki’s Castle #hydrothermal vent field 3/11
Read 11 tweets

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