Discover and read the best of Twitter Threads about #fluorescent
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#Retinal involvement in #Covid19 and possibly also in Long-Covid
There is more to #SARS2 than meets the eye:
1-Coronavirus not only infects the human retina, but can also replicate in it!
2-The so-called ‘long-Covid’ symptoms may include degenerative retinal disease. 1/
There is more to #SARS2 than meets the eye:
1-Coronavirus not only infects the human retina, but can also replicate in it!
2-The so-called ‘long-Covid’ symptoms may include degenerative retinal disease. 1/
Which cells in the retinal organoids are affected?
The researchers analyzed the organoids under a fluorescence microscope. 2/
The researchers analyzed the organoids under a fluorescence microscope. 2/
With the help of different immune markers for the different cell types of the retina & with a #fluorescent antibody against the #nucleoprotein (N-protein) of #SARS2, it was shown that mainly two cell layers of the retinal organoids were infected. 3/
After 6 months of #lockdown and #lab shutdown I spent a full day 9 am-8 pm in lab doing experiments! New #grad students in #lifesciences: There is always light 💡 and #fluorescent images at the end of the tunnel! Filing a #patent on my #invention from #phd work soon @OrganOnAChip
This is an Organ on a Chip platform that enables mimicking #tissues and #organs in a high throughput manner! The main focus will be towards developing #mucosal organs with tissue resident #immune cells and lining #epithelial cells for #testing #COVID19 treatments #covidvaccines
I recently gave a talk at #oooc2020 organized by @GVNlab at @Columbia. In the talk I demonstrated the #ease of fabrication, #functionality, and #modularity of this platform.
We’re open to #collaborate with interested #researchers! Interested to learn more:
We’re open to #collaborate with interested #researchers! Interested to learn more:
Drawing Innovation: @illumina Super-Resolution Optics
Recently, $ILMN unveiled the NextSeq 2000, a mid-throughput sequencer w/ a ~2X reduction in operating costs ($/GB).
We think the upgrades inside the NextSeq 2000 may soon enable a $100 clinical-depth human #genome.
But how?
Recently, $ILMN unveiled the NextSeq 2000, a mid-throughput sequencer w/ a ~2X reduction in operating costs ($/GB).
We think the upgrades inside the NextSeq 2000 may soon enable a $100 clinical-depth human #genome.
But how?
The cost savings come from (1) a new upfront #chemistry and (2) super-resolution optics. We think @illumina will use real-world customer data on the NextSeq 2000 to optimize 1 and 2, then possibly upgrade the #NovaSeq line.
illumina.com/systems/sequen…
illumina.com/systems/sequen…
I'm going to briefly (!) illustrate how #sequencing (*by synthesis*) works, walk through a farming analogy, then dive into some technical details. (Sources at the end)
Below is a general overview of a whole genome sequencing workflow (sample in, data out).
Below is a general overview of a whole genome sequencing workflow (sample in, data out).
