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Happy Holidays! I'm starting a #FOAMed gift exchange.
My gift to #MedTwitter is-
🎁5 reasons to continue your patient's #buprenorphine perioperatively!🎁
My gift to #MedTwitter is-
🎁5 reasons to continue your patient's #buprenorphine perioperatively!🎁
1) Turns out bup is a great analgesic, and is actually unlikely to have a ceiling dose for analgesia. Abruptly stopping someone's basal analgesic + inflicting painful stimulus = poor postop pain control!
pubmed.ncbi.nlm.nih.gov/29624528/
pubmed.ncbi.nlm.nih.gov/16547090/
pubmed.ncbi.nlm.nih.gov/20492579/
pubmed.ncbi.nlm.nih.gov/29624528/
pubmed.ncbi.nlm.nih.gov/16547090/
pubmed.ncbi.nlm.nih.gov/20492579/
2) Furthermore, bup's unique receptor profile affords a ceiling dose for resp depression, likely adding safety in the high-risk postop period. Changing to only pure mu agonists instead likely ⬆️risk for AEs
pubmed.ncbi.nlm.nih.gov/29452378/
pubmed.ncbi.nlm.nih.gov/16547090/
pubmed.ncbi.nlm.nih.gov/20492579/
pubmed.ncbi.nlm.nih.gov/29452378/
pubmed.ncbi.nlm.nih.gov/16547090/
pubmed.ncbi.nlm.nih.gov/20492579/
