Discover and read the best of Twitter Threads about #foamneo
Most recents (3)
As a follow-up to Febuary's issue, March's issue also includes numerous articles on Racial, Social & Gender Disparities in Perinatal Medicine. A #neoEBM and #neoTwitter 🧵1/
2/ Leading off are two editorials. The first, led by @JPerinatology EIC's Patrick Gallagher, provides some insight on what we can do about disparities in perinatal health. go.nature.com/3bTZsrx
3/ The 2nd editorial is by @hhburris & @Meg_Parker_MD. They say the study by @KaylaKarvonen is a call to action for providers of preterm infants in the NICU and beyond to work toward health equity. go.nature.com/30QfsET
#Bevacizumab for #ROP Rx & Neurodevelopment thread
Delighted our #metaanalysis out today in @JPerinatology
Results indicate Neurodevelopment harm associated w/ Avastin Rx
@EBNEO @waseemoddin
nature.com/articles/s4137…
rdcu.be/cbRdK #FOAMneo
1/6
Delighted our #metaanalysis out today in @JPerinatology
Results indicate Neurodevelopment harm associated w/ Avastin Rx
@EBNEO @waseemoddin
nature.com/articles/s4137…
rdcu.be/cbRdK #FOAMneo
1/6
The idea started with a dialogue by a colleague ”We don’t do lasers, they are ancient, we do avastin - simple, easy, less recurrence.”
Me: “there are long term risks - right?”
Colleague: Na, it’s ok, we already accepted & moved 🤨
2/6
Me: “there are long term risks - right?”
Colleague: Na, it’s ok, we already accepted & moved 🤨
2/6
I thought it’s good idea to pursue a #Systematicreview as the evidence is sketchy & controversial but what really pushed me to do the review is👇
Avastin can fire the brain for 60 days (#staylong) by suppressing VEGF that is crucial for brain growth
3/6
is.gd/5BE9AN
Avastin can fire the brain for 60 days (#staylong) by suppressing VEGF that is crucial for brain growth
3/6
is.gd/5BE9AN
2dary analysis of @PlaNeT2_trial out now. @KDraat @ESteyerberg @Willem_Pieter @BloodJournal #ebneo #FOAMneo #neohematol . A thread. Primary result of trial: more bleeding/death in neonates treated acc to prophylactic platelet tx threshold of 50 comp to 25. 1/3
We reanalyzed the data to look for subgroups of neonates that might benefit from the 50 threshold after all. Instead of using conventional subgroup analyses we used a more robust predicted baseline risk approach. More info? Start reading here: doi.org/10.1136/bmj.k4… 2/3
We did not identify subgroups that benefit from the 50 threshold, though model needs further improvement. Suggests prophylactic platelet tx threshold of 25 appropriate for all preterm neonates, incl those at high risk of bleed/mortality. 3/3 @sanquin @LUMC_Leiden @amsterdamumc
