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Dear #neurotwitter, we dropped this onto @biorxiv_neursci for your perusal. It's an unusual piece from my lab & I really, really enjoyed working on it with @chc1987. Here it is: Metabolically spikes serve neuronal energy homeostasis (and protect neurons). doi.org/10.1101/2022.1…
"Metabolic Spikes" is a modelling study on the origins of "spontaneous" activity in neural systems. That sort of baseline activity is ubiquitous! As a field, we accept it's there & include it in models, but why do neurons do that? Fire in the absence of input? Seems kinda weird.
More formally speaking, non-causal spiking contradicts the notion that spikes should be used for coding, and what's more, such "null spikes" seem like a waste of energy. Sort of like opening a window in an NYC apartment in the middle of winter....
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